Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   JMO16_RS10215 Genome accession   NZ_CP080566
Coordinates   2044139..2044768 (-) Length   209 a.a.
NCBI ID   WP_042109421.1    Uniprot ID   -
Organism   Staphylococcus aureus strain HL20835 isolate HL20835     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2039139..2049768
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JMO16_RS10185 (JMO16_10185) - 2039559..2040089 (-) 531 WP_000184383.1 acyl-CoA thioesterase -
  JMO16_RS10190 (JMO16_10190) - 2040179..2041435 (-) 1257 WP_001795108.1 aminopeptidase -
  JMO16_RS10195 (JMO16_10195) - 2041438..2041638 (-) 201 WP_000180460.1 DUF1128 family protein -
  JMO16_RS10200 (JMO16_10200) - 2041785..2042249 (+) 465 WP_042109418.1 low molecular weight protein-tyrosine-phosphatase -
  JMO16_RS10205 (JMO16_10205) - 2042256..2042531 (+) 276 WP_000428172.1 YtxH domain-containing protein -
  JMO16_RS10210 (JMO16_10210) - 2042809..2044026 (+) 1218 WP_000037075.1 YihY/virulence factor BrkB family protein -
  JMO16_RS10215 (JMO16_10215) vraR 2044139..2044768 (-) 630 WP_042109421.1 two-component system response regulator VraR Regulator
  JMO16_RS10220 (JMO16_10220) vraS 2044758..2045801 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  JMO16_RS10225 (JMO16_10225) liaF 2045798..2046499 (-) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  JMO16_RS10230 (JMO16_10230) - 2046514..2046900 (-) 387 WP_001110179.1 hypothetical protein -
  JMO16_RS10235 (JMO16_10235) map 2047117..2047875 (-) 759 WP_000636142.1 type I methionyl aminopeptidase -
  JMO16_RS10240 (JMO16_10240) - 2048406..2048534 (+) 129 WP_256969316.1 aromatic acid exporter family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23569.36 Da        Isoelectric Point: 5.3935

>NTDB_id=594081 JMO16_RS10215 WP_042109421.1 2044139..2044768(-) (vraR) [Staphylococcus aureus strain HL20835 isolate HL20835]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYPNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=594081 JMO16_RS10215 WP_042109421.1 2044139..2044768(-) (vraR) [Staphylococcus aureus strain HL20835 isolate HL20835]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGAAGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACCCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTCATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.522

100

0.995
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368