Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   M2894_RS00600 Genome accession   NZ_CP096976
Coordinates   121705..122295 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain 17-07187     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 116705..127295
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2894_RS00570 (M2894_00570) emrD 117187..118371 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  M2894_RS00575 (M2894_00575) ysdE 118453..118527 (+) 75 WP_211180519.1 protein YsdE -
  M2894_RS00580 (M2894_00580) tisB 118790..118879 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  M2894_RS00585 (M2894_00585) ivbL 119444..119542 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  M2894_RS00590 (M2894_00590) ilvB 119648..121336 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  M2894_RS00595 (M2894_00595) ilvN 121340..121630 (+) 291 WP_001181713.1 acetolactate synthase small subunit -
  M2894_RS00600 (M2894_00600) letA 121705..122295 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  M2894_RS00605 (M2894_00605) uhpB 122295..123797 (+) 1503 WP_001330988.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  M2894_RS00610 (M2894_00610) uhpC 123807..125126 (+) 1320 WP_001358267.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  M2894_RS00615 (M2894_00615) uhpT 125264..126655 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=593171 M2894_RS00600 WP_000633668.1 121705..122295(+) (letA) [Escherichia coli strain 17-07187]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=593171 M2894_RS00600 WP_000633668.1 121705..122295(+) (letA) [Escherichia coli strain 17-07187]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378