Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   Sta0113_RS10630 Genome accession   NZ_CP080457
Coordinates   2157883..2158512 (-) Length   209 a.a.
NCBI ID   WP_002450048.1    Uniprot ID   A0A1L8Y4G9
Organism   Staphylococcus hominis subsp. hominis strain WiKim0113     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2152883..2163512
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Sta0113_RS10600 (Sta0113_10535) - 2153586..2154119 (-) 534 WP_070813221.1 acyl-CoA thioesterase -
  Sta0113_RS10605 (Sta0113_10540) - 2154152..2155399 (-) 1248 WP_145437019.1 aminopeptidase -
  Sta0113_RS10610 (Sta0113_10545) - 2155411..2155617 (-) 207 WP_002450082.1 DUF1128 domain-containing protein -
  Sta0113_RS10615 (Sta0113_10550) - 2155759..2156223 (+) 465 WP_017175226.1 low molecular weight protein-tyrosine-phosphatase -
  Sta0113_RS10620 (Sta0113_10555) - 2156229..2156510 (+) 282 WP_002450075.1 hypothetical protein -
  Sta0113_RS10625 (Sta0113_10560) - 2156602..2157804 (+) 1203 WP_017175227.1 YihY/virulence factor BrkB family protein -
  Sta0113_RS10630 (Sta0113_10565) vraR 2157883..2158512 (-) 630 WP_002450048.1 two-component system response regulator VraR Regulator
  Sta0113_RS10635 (Sta0113_10570) vraS 2158514..2159548 (-) 1035 WP_248855239.1 sensor histidine kinase Regulator
  Sta0113_RS10640 (Sta0113_10575) liaF 2159545..2160246 (-) 702 WP_017175229.1 cell wall-active antibiotics response protein LiaF -
  Sta0113_RS10645 (Sta0113_10580) - 2160268..2160654 (-) 387 WP_145422112.1 hypothetical protein -
  Sta0113_RS10650 - 2160960..2161076 (+) 117 Protein_2056 nickel transporter NixA -
  Sta0113_RS10655 (Sta0113_10585) map 2161331..2162083 (-) 753 WP_017175231.1 type I methionyl aminopeptidase -
  Sta0113_RS10660 (Sta0113_10590) - 2162257..2163246 (+) 990 WP_017175232.1 aromatic acid exporter family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23592.26 Da        Isoelectric Point: 5.3673

>NTDB_id=592989 Sta0113_RS10630 WP_002450048.1 2157883..2158512(-) (vraR) [Staphylococcus hominis subsp. hominis strain WiKim0113]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGSSGKEAIEKAHTLNPDLILMDLLMNDMDGVEATTQIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIAEAVRKTYRGESVFEPEVLVKMRNRMKKKAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=592989 Sta0113_RS10630 WP_002450048.1 2157883..2158512(-) (vraR) [Staphylococcus hominis subsp. hominis strain WiKim0113]
ATGACGATTAAAGTATTATTTGTAGACGATCATGAAATGGTTAGAATTGGTATTTCAAGTTATTTATCTACTCAATCTGA
TATTGAAGTAGTAGGAGAAGGATCATCAGGAAAAGAGGCAATTGAAAAAGCACATACGTTAAATCCTGATTTAATTTTAA
TGGATTTGTTAATGAATGATATGGACGGTGTAGAAGCGACGACACAAATAAAAAAAGATTTGCCTCATATCAAAGTAGTC
ATGTTAACAAGTTTTATAGAAGATAAAGAAGTATATAGAGCACTTGATGCAGGGGTTGATAGTTATATATTAAAAACGAC
AAGTGCCAGTGATATTGCAGAAGCAGTTAGAAAAACATATCGTGGAGAATCTGTATTCGAGCCAGAAGTTTTAGTAAAAA
TGAGAAATAGAATGAAGAAGAAAGCAGAATTATATGAAATGCTCACTGAACGTGAAATGGAAATATTGTTATTAATTGCT
AAAGGCTATTCTAATCAAGAAATTGCCAGTGCTTCACATATTACAATTAAAACAGTAAAAACACATGTGAGTAATATTTT
AAGTAAACTAGAGGTACAAGATAGAACACAAGCGGTTATTTATGCATTCCAACATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1L8Y4G9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.737

100

0.947
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378