Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraS   Type   Regulator
Locus tag   Sta0113_RS10635 Genome accession   NZ_CP080457
Coordinates   2158514..2159548 (-) Length   344 a.a.
NCBI ID   WP_248855239.1    Uniprot ID   -
Organism   Staphylococcus hominis subsp. hominis strain WiKim0113     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2153514..2164548
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Sta0113_RS10600 (Sta0113_10535) - 2153586..2154119 (-) 534 WP_070813221.1 acyl-CoA thioesterase -
  Sta0113_RS10605 (Sta0113_10540) - 2154152..2155399 (-) 1248 WP_145437019.1 aminopeptidase -
  Sta0113_RS10610 (Sta0113_10545) - 2155411..2155617 (-) 207 WP_002450082.1 DUF1128 domain-containing protein -
  Sta0113_RS10615 (Sta0113_10550) - 2155759..2156223 (+) 465 WP_017175226.1 low molecular weight protein-tyrosine-phosphatase -
  Sta0113_RS10620 (Sta0113_10555) - 2156229..2156510 (+) 282 WP_002450075.1 hypothetical protein -
  Sta0113_RS10625 (Sta0113_10560) - 2156602..2157804 (+) 1203 WP_017175227.1 YihY/virulence factor BrkB family protein -
  Sta0113_RS10630 (Sta0113_10565) vraR 2157883..2158512 (-) 630 WP_002450048.1 two-component system response regulator VraR Regulator
  Sta0113_RS10635 (Sta0113_10570) vraS 2158514..2159548 (-) 1035 WP_248855239.1 sensor histidine kinase Regulator
  Sta0113_RS10640 (Sta0113_10575) liaF 2159545..2160246 (-) 702 WP_017175229.1 cell wall-active antibiotics response protein LiaF -
  Sta0113_RS10645 (Sta0113_10580) - 2160268..2160654 (-) 387 WP_145422112.1 hypothetical protein -
  Sta0113_RS10650 - 2160960..2161076 (+) 117 Protein_2056 nickel transporter NixA -
  Sta0113_RS10655 (Sta0113_10585) map 2161331..2162083 (-) 753 WP_017175231.1 type I methionyl aminopeptidase -
  Sta0113_RS10660 (Sta0113_10590) - 2162257..2163246 (+) 990 WP_017175232.1 aromatic acid exporter family protein -
  Sta0113_RS10665 (Sta0113_10595) - 2163291..2164010 (-) 720 WP_017175233.1 type 1 glutamine amidotransferase -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 39743.28 Da        Isoelectric Point: 5.8932

>NTDB_id=592990 Sta0113_RS10635 WP_248855239.1 2158514..2159548(-) (vraS) [Staphylococcus hominis subsp. hominis strain WiKim0113]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLVIILLCIIVGSVLAYKINQQNDWIKN
QIEHAIEGETVGINDKNIELYNETIDIYQMLVPLNQELQRLRIKTQNLTNENYNMNDIKVKKIIEDERQRLARELHDSVN
QQLFAASMMLSAIKETELEPPLNQQIPVLEKMIQESQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVIYDI
QDFKVPKGIEDHLFRITQEAISNTLRHSDGTKVTVELFNHQDYLLLRIQDNGKGFNVDEKVEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLTKEEG

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=592990 Sta0113_RS10635 WP_248855239.1 2158514..2159548(-) (vraS) [Staphylococcus hominis subsp. hominis strain WiKim0113]
ATGAATCACTATTTAAGAGCAATAGGATCCATGCTTATTTTAGTGTATAGCATGCTAACTGCGTTTTTATTTATAGATAA
AGTTTTTGTAAATATTATATATTTTCAAGGAATGTTCTATACTCAAATATTTGGTATACCTGTGTTTCTATTTCTTAATT
TAGTGATTATTTTACTTTGTATTATCGTTGGCTCTGTATTAGCTTATAAAATAAATCAGCAAAATGATTGGATAAAGAAT
CAAATTGAACACGCCATTGAAGGTGAAACGGTAGGGATTAATGATAAAAACATAGAACTATATAATGAAACAATTGATAT
TTATCAAATGTTAGTGCCTTTAAATCAAGAATTACAACGATTAAGAATCAAAACTCAAAATTTAACAAATGAAAACTACA
ATATGAATGACATTAAAGTAAAAAAAATTATAGAAGATGAGCGTCAGCGTTTAGCAAGGGAATTACACGATTCAGTAAAT
CAACAACTTTTCGCAGCAAGTATGATGTTATCAGCGATAAAAGAAACAGAACTAGAACCACCCCTTAACCAACAAATTCC
AGTACTTGAGAAAATGATACAAGAATCTCAATTAGAGATGCGAGCGCTGTTACTACATTTGCGACCTTTAGGACTCAAGG
ATAAATCATTAGGGGAAGGTATTAAAGATTTAGTCATTGATTTACAAAAGAAAGTACCTATGAAAGTCATTTATGATATA
CAAGATTTTAAAGTGCCTAAAGGAATTGAAGATCATCTATTTCGAATTACACAAGAGGCAATTTCAAATACATTAAGACA
TTCTGATGGAACTAAAGTGACAGTCGAATTATTTAATCATCAAGATTATTTATTATTAAGAATTCAAGATAATGGTAAAG
GCTTTAACGTAGATGAAAAAGTAGAACAAAGTTATGGATTGAAAAATATGAGAGAACGTGCATTAGAAATAGGTGCAACG
TTTCATATCGTATCTCTACCAGATTCAGGAACTAGAATAGAGGTAAAAGCACCTTTAACGAAAGAGGAGGGTTAA

Domains

Predicted by InterproScan.

Histidine kinase (HisKA_3)

(147-210)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(249-340)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraS Staphylococcus aureus N315

89.535

100

0.895