Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MYF74_RS15005 Genome accession   NZ_CP096837
Coordinates   3166888..3168909 (-) Length   673 a.a.
NCBI ID   WP_000042533.1    Uniprot ID   Q324B3
Organism   Escherichia coli strain PS10-3     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3161888..3173909
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MYF74_RS14975 (MYF74_14975) moaE 3162689..3163141 (-) 453 WP_000852287.1 molybdopterin synthase catalytic subunit MoaE -
  MYF74_RS14980 (MYF74_14980) moaD 3163143..3163388 (-) 246 WP_000598612.1 molybdopterin synthase sulfur carrier subunit -
  MYF74_RS14985 (MYF74_14985) moaC 3163381..3163866 (-) 486 WP_000080885.1 cyclic pyranopterin monophosphate synthase MoaC -
  MYF74_RS14990 (MYF74_14990) moaB 3163869..3164381 (-) 513 WP_000084639.1 molybdenum cofactor biosynthesis protein B -
  MYF74_RS14995 (MYF74_14995) moaA 3164403..3165392 (-) 990 WP_001295301.1 GTP 3',8-cyclase MoaA -
  MYF74_RS15000 (MYF74_15000) yvcK 3165789..3166697 (+) 909 WP_001301716.1 uridine diphosphate-N-acetylglucosamine-binding protein YvcK -
  MYF74_RS15005 (MYF74_15005) uvrB 3166888..3168909 (-) 2022 WP_000042533.1 excinuclease ABC subunit UvrB Machinery gene
  MYF74_RS15010 (MYF74_15010) bioD 3169488..3170165 (-) 678 WP_053274161.1 dethiobiotin synthase -
  MYF74_RS15015 (MYF74_15015) bioC 3170158..3170913 (-) 756 WP_000246791.1 malonyl-ACP O-methyltransferase BioC -
  MYF74_RS15020 (MYF74_15020) bioF 3170900..3172054 (-) 1155 WP_000118854.1 8-amino-7-oxononanoate synthase -
  MYF74_RS15025 (MYF74_15025) bioB 3172051..3173091 (-) 1041 WP_000951213.1 biotin synthase BioB -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76226.06 Da        Isoelectric Point: 4.8843

>NTDB_id=590969 MYF74_RS15005 WP_000042533.1 3166888..3168909(-) (uvrB) [Escherichia coli strain PS10-3]
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=590969 MYF74_RS15005 WP_000042533.1 3166888..3168909(-) (uvrB) [Escherichia coli strain PS10-3]
ATGAGTAAACCGTTCAAACTGAATTCCGCTTTTAAACCTTCTGGCGATCAGCCAGAGGCGATTCGACGTCTCGAAGAGGG
GCTGGAAGATGGCCTGGCGCACCAGACGTTACTTGGCGTGACTGGCTCCGGGAAAACCTTCACCATTGCCAATGTCATTG
CTGACCTTCAGCGCCCTACCATGGTACTTGCGCCCAACAAAACGCTGGCGGCCCAGCTGTATGGCGAAATGAAAGAGTTC
TTCCCGGAAAACGCGGTGGAATATTTCGTCTCCTACTACGACTACTATCAGCCGGAAGCCTATGTACCGAGTTCTGACAC
CTTCATTGAGAAAGATGCCTCGGTAAACGAACATATCGAACAGATGCGTTTGTCCGCCACCAAAGCGATGCTGGAGCGAC
GTGATGTGGTTGTGGTGGCGTCTGTTTCCGCGATTTATGGTCTGGGCGATCCTGATTTATATCTCAAGATGATGCTCCAT
CTCACGGTCGGTATGATTATCGATCAGCGCGCGATTCTGCGCCGATTGGCGGAGCTGCAATACGCTCGTAATGATCAGGC
ATTCCAGCGCGGTACTTTCCGCGTTCGTGGCGAGGTGATTGATATATTCCCGGCAGAATCGGATGACATTGCACTTCGCG
TGGAACTGTTTGACGAGGAAGTGGAACGATTGTCGTTATTTGACCCGCTGACCGGGCAGATTGTTTCCACTATTCCACGT
TTTACCATCTACCCGAAAACGCACTACGTCACACCGCGCGAGCGCATCGTACAGGCGATGGAGGAGATCAAAGAAGAGCT
GGCCGCCAGACGCAAAGTGCTGTTGGAAAACAACAAACTGCTGGAAGAGCAGCGGCTGACCCAGCGTACCCAGTTTGATC
TGGAGATGATGAACGAGCTGGGATACTGTTCGGGGATTGAAAACTACTCGCGCTTCCTCTCCGGTCGTGGACCGGGTGAG
CCACCGCCGACGCTGTTTGATTACCTGCCTGCCGATGGGCTGCTGGTGGTCGATGAATCTCACGTCACCATTCCACAAAT
TGGCGGCATGTATCGCGGTGACCGGGCGCGTAAAGAGACACTGGTGGAGTACGGCTTCCGCCTGCCATCAGCGCTGGATA
ACCGTCCGCTGAAATTTGAAGAGTTCGAAGCATTAGCGCCGCAAACCATCTATGTTTCGGCGACGCCGGGTAATTACGAG
CTGGAAAAATCCGGCGGCGATGTGGTGGATCAGGTGGTGCGTCCAACCGGATTGCTTGACCCGATTATCGAAGTGCGGCC
GGTGGCGACACAGGTTGATGATCTTCTTTCGGAGATTCGTCAGCGAGCGGCAATTAACGAACGCGTACTGGTCACCACAC
TGACCAAGCGGATGGCAGAAGATCTTACCGAATATCTCGAAGAACACGGCGAGCGCGTGCGTTATCTTCACTCAGATATC
GACACCGTCGAACGTATGGAGATTATCCGCGACTTGCGTCTGGGCGAGTTCGACGTGCTGGTGGGGATCAACTTACTGCG
CGAAGGTCTGGATATGCCGGAGGTTTCGCTGGTGGCGATCCTCGACGCTGACAAAGAAGGCTTCCTGCGTTCCGAACGTT
CGTTGATCCAGACCATTGGTCGTGCGGCACGTAACGTTAACGGTAAAGCGATTCTCTACGGCGATAAGATCACCCCATCA
ATGGCGAAAGCGATTGGCGAAACCGAACGTCGCCGCGAGAAACAGCAGAAGTACAACGAGGAACACGGCATTACGCCGCA
AGGCTTGAACAAGAAAGTGGTCGATATCCTGGCGCTGGGGCAGAACATCGCCAAAACCAAAGCGAAGGGCAGAGGAAAAT
CGCGCCCGATTGTTGAGCCGGATAATGTGCCGATGGATATGTCGCCTAAAGCGTTGCAACAGAAAATCCATGAGCTGGAA
GGGTTAATGATGCAACACGCGCAGAATCTGGAGTTCGAAGAAGCGGCACAAATTCGTGACCAGTTGCATCAGCTGCGTGA
ATTGTTTATCGCGGCTTCGTGA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(159-249)

UvrB/uvrC motif (UVR)

(634-667)

Ultra-violet resistance protein B (UvrB)

(552-593)

Type III restriction enzyme, res subunit (ResIII)

(13-92)

Helicase conserved C-terminal domain (Helicase_C)

(436-544)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q324B3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

56.372

99.108

0.559
  uvrB Streptococcus pneumoniae R6

56.222

99.108

0.557
  uvrB Streptococcus pneumoniae D39

56.222

99.108

0.557