Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MYF74_RS09105 Genome accession   NZ_CP096837
Coordinates   1934529..1936361 (+) Length   610 a.a.
NCBI ID   WP_028132062.1    Uniprot ID   -
Organism   Escherichia coli strain PS10-3     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1929529..1941361
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MYF74_RS09070 (MYF74_09070) dcyD 1929755..1930741 (+) 987 WP_025652951.1 D-cysteine desulfhydrase -
  MYF74_RS09075 (MYF74_09075) tcyL 1930756..1931424 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  MYF74_RS09080 (MYF74_09080) tcyN 1931421..1932173 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  MYF74_RS09085 (MYF74_09085) sdiA 1932403..1933125 (+) 723 WP_001154269.1 transcriptional regulator SdiA -
  MYF74_RS09090 (MYF74_09090) yecF 1933193..1933417 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  MYF74_RS09095 (MYF74_09095) yecU 1933404..1933580 (-) 177 WP_000590347.1 protein YecU -
  MYF74_RS23085 - 1933663..1933734 (-) 72 Protein_1782 transcriptional regulator -
  MYF74_RS09100 (MYF74_09100) letA 1933876..1934532 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  MYF74_RS09105 (MYF74_09105) uvrC 1934529..1936361 (+) 1833 WP_028132062.1 excinuclease ABC subunit UvrC Machinery gene
  MYF74_RS09110 (MYF74_09110) pgsA 1936418..1936966 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MYF74_RS09130 (MYF74_09130) - 1937662..1938402 (-) 741 WP_022581686.1 hypothetical protein -
  MYF74_RS23090 - 1938483..1938959 (+) 477 Protein_1787 Arm DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68197.04 Da        Isoelectric Point: 9.3687

>NTDB_id=590957 MYF74_RS09105 WP_028132062.1 1934529..1936361(+) (uvrC) [Escherichia coli strain PS10-3]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASHNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=590957 MYF74_RS09105 WP_028132062.1 1934529..1936361(+) (uvrC) [Escherichia coli strain PS10-3]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCTGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAATGTTTTGCTACGCGATGATAAATCATATCCTTTTATCTTCCT
GAGTGGCGATACCCACCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCATGTCTGCAATATCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTTAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTGATTAGCCGTA
TGGAAACTGCCAGTCACAATCTGGAGTTTGAAGAAGCGGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAGTTTGTTTCCAATACCGGCGACGACCTTGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTTGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTGGAAACCTTCGTAGGACAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATAGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGACTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGTGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACAGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TCGACGACAGTAAGATCCCGGATGTGATACTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTCAGTTTGCCGCCAGATTCTCCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCTCACGATCACGCGATTGGTGGGCACCGTAAGAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

UvrB/uvrC motif (UVR)

(205-237)

Helix-hairpin-helix domain (HHH_5)

(558-609)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.727

99.508

0.375
  uvrC Streptococcus pneumoniae R6

37.397

99.508

0.372
  uvrC Streptococcus pneumoniae D39

37.397

99.508

0.372