Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MYF74_RS09100 Genome accession   NZ_CP096837
Coordinates   1933876..1934532 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain PS10-3     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1928876..1939532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MYF74_RS09070 (MYF74_09070) dcyD 1929755..1930741 (+) 987 WP_025652951.1 D-cysteine desulfhydrase -
  MYF74_RS09075 (MYF74_09075) tcyL 1930756..1931424 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  MYF74_RS09080 (MYF74_09080) tcyN 1931421..1932173 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  MYF74_RS09085 (MYF74_09085) sdiA 1932403..1933125 (+) 723 WP_001154269.1 transcriptional regulator SdiA -
  MYF74_RS09090 (MYF74_09090) yecF 1933193..1933417 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  MYF74_RS09095 (MYF74_09095) yecU 1933404..1933580 (-) 177 WP_000590347.1 protein YecU -
  MYF74_RS23085 - 1933663..1933734 (-) 72 Protein_1782 transcriptional regulator -
  MYF74_RS09100 (MYF74_09100) letA 1933876..1934532 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  MYF74_RS09105 (MYF74_09105) uvrC 1934529..1936361 (+) 1833 WP_028132062.1 excinuclease ABC subunit UvrC Machinery gene
  MYF74_RS09110 (MYF74_09110) pgsA 1936418..1936966 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MYF74_RS09130 (MYF74_09130) - 1937662..1938402 (-) 741 WP_022581686.1 hypothetical protein -
  MYF74_RS23090 - 1938483..1938959 (+) 477 Protein_1787 Arm DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=590956 MYF74_RS09100 WP_000611328.1 1933876..1934532(+) (letA) [Escherichia coli strain PS10-3]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=590956 MYF74_RS09100 WP_000611328.1 1933876..1934532(+) (letA) [Escherichia coli strain PS10-3]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482