Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   MYF74_RS03535 Genome accession   NZ_CP096837
Coordinates   738423..739082 (-) Length   219 a.a.
NCBI ID   WP_001221493.1    Uniprot ID   Q3YXL4
Organism   Escherichia coli strain PS10-3     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 733423..744082
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MYF74_RS03510 (MYF74_03510) yqiA 733491..734072 (+) 582 WP_000105733.1 esterase YqiA -
  MYF74_RS03515 (MYF74_03515) parE 734101..735993 (+) 1893 WP_000195274.1 DNA topoisomerase IV subunit B -
  MYF74_RS03520 (MYF74_03520) ygiN 736041..736355 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  MYF74_RS03525 (MYF74_03525) mdaB 736386..736967 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  MYF74_RS03530 (MYF74_03530) qseC 737077..738426 (-) 1350 WP_000673365.1 quorum sensing histidine kinase QseC -
  MYF74_RS03535 (MYF74_03535) ciaR 738423..739082 (-) 660 WP_001221493.1 quorum sensing response regulator transcription factor QseB Regulator
  MYF74_RS03540 (MYF74_03540) ygiW 739234..739626 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  MYF74_RS03545 (MYF74_03545) ygiV 739679..740161 (+) 483 WP_000183494.1 GyrI-like domain-containing protein -
  MYF74_RS03550 (MYF74_03550) ygiS 740270..741877 (+) 1608 WP_248748164.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24687.63 Da        Isoelectric Point: 6.9850

>NTDB_id=590933 MYF74_RS03535 WP_001221493.1 738423..739082(-) (ciaR) [Escherichia coli strain PS10-3]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=590933 MYF74_RS03535 WP_001221493.1 738423..739082(-) (ciaR) [Escherichia coli strain PS10-3]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAGGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3YXL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365