Detailed information
Bioinformatically predicted
Overview
| Name | pilX | Type | Machinery gene |
| Locus tag | KZH42_RS05320 | Genome accession | NZ_CP079941 |
| Coordinates | 1048163..1048636 (+) | Length | 157 a.a. |
| NCBI ID | WP_002225356.1 | Uniprot ID | - |
| Organism | Neisseria meningitidis strain C311 | ||
| Function | assembly of type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 1046022..1062258 | 1048163..1048636 | within | 0 |
Gene organization within MGE regions
Location: 1046022..1062258
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KZH42_RS05305 (KZH42_05305) | pilV | 1046028..1046648 (+) | 621 | WP_002225360.1 | type IV pilus modification protein PilV | Machinery gene |
| KZH42_RS05310 (KZH42_05310) | pilJ | 1046645..1047586 (+) | 942 | WP_002244084.1 | PilW family protein | Machinery gene |
| KZH42_RS05315 (KZH42_05315) | pilK | 1047565..1048158 (+) | 594 | WP_002244085.1 | PilX N-terminal domain-containing pilus assembly protein | Machinery gene |
| KZH42_RS05320 (KZH42_05320) | pilX | 1048163..1048636 (+) | 474 | WP_002225356.1 | PilX family type IV pilin | Machinery gene |
| KZH42_RS05325 (KZH42_05325) | - | 1050405..1050773 (-) | 369 | Protein_1034 | AzlC family ABC transporter permease | - |
| KZH42_RS05330 (KZH42_05330) | dut | 1050973..1051425 (+) | 453 | WP_002225353.1 | dUTP diphosphatase | - |
| KZH42_RS05335 (KZH42_05335) | dapC | 1051503..1052690 (+) | 1188 | WP_002225352.1 | succinyldiaminopimelate transaminase | - |
| KZH42_RS11995 | - | 1052779..1052904 (+) | 126 | Protein_1037 | IS5/IS1182 family transposase | - |
| KZH42_RS05340 (KZH42_05340) | yaaA | 1052953..1053732 (+) | 780 | WP_002225351.1 | peroxide stress protein YaaA | - |
| KZH42_RS05355 (KZH42_05355) | - | 1054261..1055333 (+) | 1073 | Protein_1039 | tyrosine-type recombinase/integrase | - |
| KZH42_RS05360 (KZH42_05360) | - | 1055446..1055826 (+) | 381 | WP_002220683.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| KZH42_RS05365 (KZH42_05365) | - | 1056374..1056730 (+) | 357 | WP_002223441.1 | DUF4760 domain-containing protein | - |
| KZH42_RS05370 (KZH42_05370) | - | 1057599..1058516 (+) | 918 | WP_002219437.1 | KilA-N domain-containing protein | - |
| KZH42_RS05375 (KZH42_05375) | - | 1058574..1058783 (-) | 210 | WP_002220687.1 | hypothetical protein | - |
| KZH42_RS05380 (KZH42_05380) | - | 1058780..1058920 (-) | 141 | WP_002225349.1 | hypothetical protein | - |
| KZH42_RS05385 (KZH42_05385) | - | 1058920..1059111 (-) | 192 | WP_002219435.1 | type ISP restriction/modification enzyme | - |
| KZH42_RS05390 (KZH42_05390) | - | 1059114..1059407 (-) | 294 | WP_002220689.1 | hypothetical protein | - |
| KZH42_RS05395 (KZH42_05395) | - | 1059404..1059664 (-) | 261 | WP_002223443.1 | NGO1622 family putative holin | - |
| KZH42_RS05400 (KZH42_05400) | - | 1059699..1059914 (-) | 216 | WP_002219434.1 | hypothetical protein | - |
| KZH42_RS05405 (KZH42_05405) | - | 1059984..1060838 (-) | 855 | WP_002219433.1 | YfdQ family protein | - |
| KZH42_RS05410 (KZH42_05410) | - | 1060863..1061222 (-) | 360 | WP_002219432.1 | hypothetical protein | - |
| KZH42_RS05415 (KZH42_05415) | - | 1061290..1061490 (-) | 201 | WP_002219431.1 | hypothetical protein | - |
| KZH42_RS05420 (KZH42_05420) | - | 1061734..1062159 (-) | 426 | WP_002219430.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 157 a.a. Molecular weight: 17521.30 Da Isoelectric Point: 9.4258
>NTDB_id=590376 KZH42_RS05320 WP_002225356.1 1048163..1048636(+) (pilX) [Neisseria meningitidis strain C311]
MEQKGFTLIEMMIVVAILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNISKQFILKNPLDDNQTIENKLEIFVSGYKM
NPKIAKKYSVSVKFVDKEKSRAYRLVGVPKAGTGYTLSVWMNSVGDGYKCRDAASAQAHLETLSSDVGCEAFSNRKK
MEQKGFTLIEMMIVVAILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNISKQFILKNPLDDNQTIENKLEIFVSGYKM
NPKIAKKYSVSVKFVDKEKSRAYRLVGVPKAGTGYTLSVWMNSVGDGYKCRDAASAQAHLETLSSDVGCEAFSNRKK
Nucleotide
Download Length: 474 bp
>NTDB_id=590376 KZH42_RS05320 WP_002225356.1 1048163..1048636(+) (pilX) [Neisseria meningitidis strain C311]
ATGGAACAAAAAGGGTTTACATTGATTGAGATGATGATAGTCGTCGCGATACTCGGCATTATCAGCGTCATTGCCATACC
TTCTTATCAAAGTTATATTGAAAAAGGCTATCAGTCCCAGCTTTATACGGAGATGGTCGGTATCAACAATATTTCCAAAC
AGTTTATTTTGAAAAATCCCCTGGACGATAATCAGACCATCGAGAACAAACTGGAAATATTTGTCTCAGGCTATAAGATG
AATCCGAAAATTGCCAAAAAATATAGTGTTTCGGTAAAGTTTGTCGATAAGGAAAAATCAAGGGCATACAGGTTGGTCGG
CGTTCCGAAGGCGGGGACGGGTTATACTTTGTCGGTATGGATGAACAGCGTGGGCGACGGATACAAATGCCGTGATGCCG
CTTCTGCCCAAGCCCATTTGGAGACCTTGTCCTCAGATGTCGGCTGTGAAGCCTTCTCTAATCGTAAAAAATAA
ATGGAACAAAAAGGGTTTACATTGATTGAGATGATGATAGTCGTCGCGATACTCGGCATTATCAGCGTCATTGCCATACC
TTCTTATCAAAGTTATATTGAAAAAGGCTATCAGTCCCAGCTTTATACGGAGATGGTCGGTATCAACAATATTTCCAAAC
AGTTTATTTTGAAAAATCCCCTGGACGATAATCAGACCATCGAGAACAAACTGGAAATATTTGTCTCAGGCTATAAGATG
AATCCGAAAATTGCCAAAAAATATAGTGTTTCGGTAAAGTTTGTCGATAAGGAAAAATCAAGGGCATACAGGTTGGTCGG
CGTTCCGAAGGCGGGGACGGGTTATACTTTGTCGGTATGGATGAACAGCGTGGGCGACGGATACAAATGCCGTGATGCCG
CTTCTGCCCAAGCCCATTTGGAGACCTTGTCCTCAGATGTCGGCTGTGAAGCCTTCTCTAATCGTAAAAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilX | Neisseria meningitidis 8013 |
92.994 |
100 |
0.93 |
| pilL | Neisseria gonorrhoeae MS11 |
88.535 |
100 |
0.885 |