Detailed information    

insolico Bioinformatically predicted

Overview


Name   pilK   Type   Machinery gene
Locus tag   KZH42_RS05315 Genome accession   NZ_CP079941
Coordinates   1047565..1048158 (+) Length   197 a.a.
NCBI ID   WP_002244085.1    Uniprot ID   Q9JZV1
Organism   Neisseria meningitidis strain C311     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1046022..1062258 1047565..1048158 within 0


Gene organization within MGE regions


Location: 1046022..1062258
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KZH42_RS05305 (KZH42_05305) pilV 1046028..1046648 (+) 621 WP_002225360.1 type IV pilus modification protein PilV Machinery gene
  KZH42_RS05310 (KZH42_05310) pilJ 1046645..1047586 (+) 942 WP_002244084.1 PilW family protein Machinery gene
  KZH42_RS05315 (KZH42_05315) pilK 1047565..1048158 (+) 594 WP_002244085.1 PilX N-terminal domain-containing pilus assembly protein Machinery gene
  KZH42_RS05320 (KZH42_05320) pilX 1048163..1048636 (+) 474 WP_002225356.1 PilX family type IV pilin Machinery gene
  KZH42_RS05325 (KZH42_05325) - 1050405..1050773 (-) 369 Protein_1034 AzlC family ABC transporter permease -
  KZH42_RS05330 (KZH42_05330) dut 1050973..1051425 (+) 453 WP_002225353.1 dUTP diphosphatase -
  KZH42_RS05335 (KZH42_05335) dapC 1051503..1052690 (+) 1188 WP_002225352.1 succinyldiaminopimelate transaminase -
  KZH42_RS11995 - 1052779..1052904 (+) 126 Protein_1037 IS5/IS1182 family transposase -
  KZH42_RS05340 (KZH42_05340) yaaA 1052953..1053732 (+) 780 WP_002225351.1 peroxide stress protein YaaA -
  KZH42_RS05355 (KZH42_05355) - 1054261..1055333 (+) 1073 Protein_1039 tyrosine-type recombinase/integrase -
  KZH42_RS05360 (KZH42_05360) - 1055446..1055826 (+) 381 WP_002220683.1 type II toxin-antitoxin system PemK/MazF family toxin -
  KZH42_RS05365 (KZH42_05365) - 1056374..1056730 (+) 357 WP_002223441.1 DUF4760 domain-containing protein -
  KZH42_RS05370 (KZH42_05370) - 1057599..1058516 (+) 918 WP_002219437.1 KilA-N domain-containing protein -
  KZH42_RS05375 (KZH42_05375) - 1058574..1058783 (-) 210 WP_002220687.1 hypothetical protein -
  KZH42_RS05380 (KZH42_05380) - 1058780..1058920 (-) 141 WP_002225349.1 hypothetical protein -
  KZH42_RS05385 (KZH42_05385) - 1058920..1059111 (-) 192 WP_002219435.1 type ISP restriction/modification enzyme -
  KZH42_RS05390 (KZH42_05390) - 1059114..1059407 (-) 294 WP_002220689.1 hypothetical protein -
  KZH42_RS05395 (KZH42_05395) - 1059404..1059664 (-) 261 WP_002223443.1 NGO1622 family putative holin -
  KZH42_RS05400 (KZH42_05400) - 1059699..1059914 (-) 216 WP_002219434.1 hypothetical protein -
  KZH42_RS05405 (KZH42_05405) - 1059984..1060838 (-) 855 WP_002219433.1 YfdQ family protein -
  KZH42_RS05410 (KZH42_05410) - 1060863..1061222 (-) 360 WP_002219432.1 hypothetical protein -
  KZH42_RS05415 (KZH42_05415) - 1061290..1061490 (-) 201 WP_002219431.1 hypothetical protein -
  KZH42_RS05420 (KZH42_05420) - 1061734..1062159 (-) 426 WP_002219430.1 hypothetical protein -

Sequence


Protein


Download         Length: 197 a.a.        Molecular weight: 21699.65 Da        Isoelectric Point: 6.3911

>NTDB_id=590375 KZH42_RS05315 WP_002244085.1 1047565..1048158(+) (pilK) [Neisseria meningitidis strain C311]
MRKQNTLTGIPTSDGQRGFALFIVLMVMIVVAFLVVTAAQSYNTEQRISANESDRKLALSLAEAALREGELQVLDLEYDT
DSKVTFSENCGKGLCAAVNVRTNNDNEEAFDNIVVQGKPTVEAVKRSCPANSTDLCIDKKGMEYKKGTRSVSKMPRYIIE
YLGVKNGENVYRVTAKAWGKNANTVVVLQSYVSNNDE

Nucleotide


Download         Length: 594 bp        

>NTDB_id=590375 KZH42_RS05315 WP_002244085.1 1047565..1048158(+) (pilK) [Neisseria meningitidis strain C311]
ATGCGCAAACAGAACACTTTGACGGGAATCCCGACTTCTGACGGACAGAGGGGGTTTGCACTGTTTATCGTGCTGATGGT
GATGATCGTCGTGGCTTTTTTGGTTGTAACTGCCGCGCAGTCTTACAATACCGAGCAGCGGATCAGTGCCAACGAATCAG
ACAGGAAATTGGCTTTGTCTTTGGCCGAGGCGGCTTTGCGGGAAGGCGAACTTCAGGTTTTGGATTTGGAATATGATACG
GACAGTAAGGTTACATTTAGCGAAAACTGTGGAAAAGGTCTGTGTGCCGCAGTGAATGTGCGGACAAATAATGATAATGA
AGAGGCTTTTGACAATATCGTGGTGCAAGGCAAGCCCACCGTTGAGGCGGTGAAGCGTTCTTGCCCTGCAAATTCTACCG
ACCTGTGCATTGACAAGAAAGGGATGGAATATAAGAAAGGCACGAGAAGCGTCAGCAAAATGCCACGTTATATTATCGAA
TATTTGGGCGTGAAGAACGGAGAAAATGTTTATCGGGTTACTGCCAAGGCTTGGGGTAAGAATGCCAATACCGTGGTCGT
CCTTCAATCTTATGTAAGCAATAATGATGAGTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q9JZV1

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilK Neisseria gonorrhoeae MS11

86.634

100

0.888