Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   KZH43_RS09225 Genome accession   NZ_CP079923
Coordinates   1821511..1822464 (-) Length   317 a.a.
NCBI ID   WP_000345135.1    Uniprot ID   A0A2U3RW99
Organism   Streptococcus pneumoniae strain Rx1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1816511..1827464
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KZH43_RS09200 (KZH43_09195) - 1817272..1817895 (-) 624 WP_000932644.1 hypothetical protein -
  KZH43_RS09205 (KZH43_09200) jag 1817946..1818932 (-) 987 WP_000260012.1 RNA-binding cell elongation regulator Jag/EloR -
  KZH43_RS09210 (KZH43_09205) - 1818951..1819775 (-) 825 WP_220041240.1 membrane protein insertase YidC -
  KZH43_RS09215 (KZH43_09210) rnpA 1819750..1820121 (-) 372 WP_000739246.1 ribonuclease P protein component -
  KZH43_RS10715 - 1820138..1820269 (-) 132 WP_000768904.1 hypothetical protein -
  KZH43_RS09220 (KZH43_09215) - 1820270..1821460 (-) 1191 WP_000167757.1 acetate kinase -
  KZH43_RS09225 (KZH43_09220) comYH 1821511..1822464 (-) 954 WP_000345135.1 class I SAM-dependent methyltransferase Machinery gene
  KZH43_RS09230 (KZH43_09225) - 1822525..1823119 (-) 595 Protein_1826 class I SAM-dependent methyltransferase -
  KZH43_RS09235 (KZH43_09230) comGG/cglG 1823256..1823669 (-) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  KZH43_RS09240 (KZH43_09235) comGF/cglF 1823647..1824108 (-) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  KZH43_RS09245 (KZH43_09240) comGE/cglE 1824071..1824373 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  KZH43_RS09250 (KZH43_09245) comGD/cglD 1824336..1824740 (-) 405 WP_000588026.1 competence type IV pilus minor pilin ComGD Machinery gene
  KZH43_RS09255 (KZH43_09250) comGC/cglC 1824733..1825059 (-) 327 WP_000738626.1 comG operon protein ComGC Machinery gene
  KZH43_RS09260 (KZH43_09255) comGB/cglB 1825061..1826077 (-) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  KZH43_RS09265 (KZH43_09260) comGA/cglA/cilD 1826025..1826966 (-) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  KZH43_RS09270 (KZH43_09265) - 1827042..1827407 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35756.99 Da        Isoelectric Point: 4.2748

>NTDB_id=590196 KZH43_RS09225 WP_000345135.1 1821511..1822464(-) (comYH) [Streptococcus pneumoniae strain Rx1]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKENNQTLKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGAIFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=590196 KZH43_RS09225 WP_000345135.1 1821511..1822464(-) (comYH) [Streptococcus pneumoniae strain Rx1]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAATAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAGGAGAACAATC
AAACCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTATTTTCTTGACCTCGCTTACTAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGCCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTCGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2U3RW99

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536