Detailed information NTG0590081

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: KZH40_RS08130
• Genome accession: NZ_CP079921
• Coordinates: 1739461..1740117 (+)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain P1875
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 1734461..1745117

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KZH40_RS08085 (KZH40_08140)	rplP	1734532..1734942 (-)	411	WP_005599294.1	50S ribosomal protein L16	-
KZH40_RS08090 (KZH40_08145)	rpsC	1734956..1735663 (-)	708	WP_005599293.1	30S ribosomal protein S3	-
KZH40_RS08095 (KZH40_08150)	rplV	1735682..1736014 (-)	333	WP_005599292.1	50S ribosomal protein L22	-
KZH40_RS08100 (KZH40_08155)	rpsS	1736025..1736300 (-)	276	WP_005539416.1	30S ribosomal protein S19	-
KZH40_RS08105 (KZH40_08160)	rplB	1736328..1737149 (-)	822	WP_005599291.1	50S ribosomal protein L2	-
KZH40_RS08110 (KZH40_08165)	rplW	1737170..1737475 (-)	306	WP_005599290.1	50S ribosomal protein L23	-
KZH40_RS08115 (KZH40_08170)	rplD	1737472..1738074 (-)	603	WP_005599282.1	50S ribosomal protein L4	-
KZH40_RS08120 (KZH40_08175)	rplC	1738090..1738716 (-)	627	WP_005599280.1	50S ribosomal protein L3	-
KZH40_RS08125 (KZH40_08180)	rpsJ	1738742..1739053 (-)	312	WP_001181005.1	30S ribosomal protein S10	-
KZH40_RS08130 (KZH40_08185)	sxy/tfoX	1739461..1740117 (+)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
KZH40_RS08135 (KZH40_08190)	fumC	1740272..1741666 (+)	1395	WP_005599273.1	class II fumarate hydratase	-
KZH40_RS08140 (KZH40_08195)	nagA	1741815..1742960 (-)	1146	WP_237606059.1	N-acetylglucosamine-6-phosphate deacetylase	-
KZH40_RS08145 (KZH40_08200)	nagB	1743012..1743815 (-)	804	WP_005602606.1	glucosamine-6-phosphate deaminase	-
KZH40_RS08150 (KZH40_08205)	nanA	1743865..1744743 (-)	879	WP_005599265.1	N-acetylneuraminate lyase	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=590081 KZH40_RS08130 WP_005609196.1 1739461..1740117(+) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain P1875]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=590081 KZH40_RS08130 WP_005609196.1 1739461..1740117(+) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain P1875]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376