Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   LPB404_RS00630 Genome accession   NZ_CP079821
Coordinates   142410..144563 (-) Length   717 a.a.
NCBI ID   WP_219074795.1    Uniprot ID   -
Organism   Streptococcus rubneri strain LPB0404     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 137410..149563
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPB404_RS00615 (LPB404_00615) - 137516..140311 (-) 2796 WP_219074794.1 YhgE/Pip domain-containing protein -
  LPB404_RS00620 (LPB404_00620) - 140447..140983 (+) 537 WP_125374688.1 TetR/AcrR family transcriptional regulator -
  LPB404_RS00625 (LPB404_00625) comB 141021..142382 (-) 1362 WP_125374689.1 bacteriocin secretion accessory protein Regulator
  LPB404_RS00630 (LPB404_00630) comA 142410..144563 (-) 2154 WP_219074795.1 peptide cleavage/export ABC transporter ComA Regulator
  LPB404_RS00635 (LPB404_00635) rpsD 144847..145458 (-) 612 WP_003009175.1 30S ribosomal protein S4 -
  LPB404_RS00640 (LPB404_00640) - 146042..146314 (-) 273 WP_006595358.1 Veg family protein -
  LPB404_RS00645 (LPB404_00645) dnaB 146318..147673 (-) 1356 WP_219074796.1 replicative DNA helicase -
  LPB404_RS00650 (LPB404_00650) rplI 147698..148150 (-) 453 WP_219074797.1 50S ribosomal protein L9 -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 81050.66 Da        Isoelectric Point: 8.5493

>NTDB_id=589720 LPB404_RS00630 WP_219074795.1 142410..144563(-) (comA) [Streptococcus rubneri strain LPB0404]
MGFKKKHYRQQVDMRDCGVAALAMVFGYYGSYYSLASLREKAKTTADGTTALGLVKVAEELGFETRAFRADRTLFDLEGV
TYPLIVHVIKDGRLPHYYVVYKKDKKHLYVADPDPKVKMTKLTIEEFEKEWTGIVIALAPTPAYQPSKEKKNGLLDFVPL
LFKQRQLVLHIVLATLLVTLINIVGSYYLQSIIDTYVPDQMKQTLTVISLGLIVVYILQQVLTYAQDYLLLVLGQRLSID
VILSYIKHVFQLPMSFFATRRTGEVVSRFTDANRIIDALASTLLSIFLDLSIVLILSVVLFSQNAHLFFLTILLLPIYAV
IIFAFMKPFERLNNETMEANSVLSSSIIEDINGIETIKSLTSERSRYQKIDSEFVDYLKKSFAMSKAESLQKGLKHLAQL
ILNVLVLWMGAHLVMKQELSLGQLITYNTLLVYFTGPLENLINLQTKLQAARVANTRLNEVYLIDSEFAEKKPLQEREAL
DGDLVFEGVDYKYGFGANVLTDINLRIKKGSKVSFVGISGSGKTTLAKMMVNFYQPHKGTIRLGGRDIQQVDKTLLRQQI
NYLPQQPYVFNGTILENLLLGAREGTSQEDILRAVEIAGIREDIERMPLNYQTELTTDGMGISGGQRQRIALARALLTDA
PILILDEATSSLDILTEKKIVDRLMALDKTIIFIAHRLTIAERSEKVFLMDQGRLMEEGSHEELLKKNGYYSHLVTC

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=589720 LPB404_RS00630 WP_219074795.1 142410..144563(-) (comA) [Streptococcus rubneri strain LPB0404]
ATGGGATTTAAGAAAAAACATTATCGCCAACAAGTTGACATGAGAGACTGTGGTGTTGCAGCTTTAGCCATGGTCTTTGG
CTACTATGGATCATACTATTCTTTAGCTAGTCTGCGGGAGAAGGCAAAAACGACTGCAGATGGAACGACCGCCTTAGGTC
TGGTCAAGGTGGCTGAGGAGTTGGGATTTGAGACACGCGCCTTCCGAGCAGATCGCACACTTTTTGACTTGGAAGGAGTG
ACCTATCCCTTGATTGTCCACGTGATCAAGGATGGGCGTCTCCCTCATTATTACGTAGTGTATAAGAAAGATAAAAAACA
TCTTTACGTAGCAGATCCAGATCCAAAAGTAAAGATGACCAAATTGACGATCGAAGAGTTTGAAAAGGAATGGACAGGGA
TTGTCATTGCCTTGGCCCCGACTCCGGCCTATCAACCTAGTAAGGAAAAGAAAAATGGGCTCCTAGACTTTGTCCCTCTT
TTGTTTAAACAGCGACAATTGGTCCTTCATATTGTTCTTGCAACTTTATTGGTAACCCTTATCAATATTGTTGGTTCTTA
CTACCTACAATCAATTATTGATACCTATGTGCCTGATCAGATGAAGCAGACCTTGACTGTGATTTCACTAGGTTTGATTG
TGGTTTACATCTTACAGCAAGTCCTCACCTACGCGCAAGATTACTTGCTCCTTGTTTTAGGCCAACGCTTGTCTATTGAT
GTCATTCTGTCCTATATTAAGCATGTTTTTCAGTTGCCCATGAGTTTCTTTGCAACTCGACGGACAGGGGAAGTGGTGTC
GCGTTTTACAGATGCCAACCGCATTATTGATGCTCTGGCTAGTACGCTGCTTTCAATCTTTTTGGATCTTTCCATCGTTC
TGATTTTATCAGTAGTCCTGTTTAGTCAAAATGCTCATCTCTTTTTCTTGACCATTCTCTTGCTGCCGATTTATGCGGTC
ATTATTTTTGCCTTTATGAAACCTTTCGAGCGCTTAAATAATGAAACCATGGAAGCCAATAGTGTCTTGTCTTCTTCTAT
TATCGAAGATATCAATGGGATTGAAACCATCAAGTCTTTGACCAGTGAACGCAGTCGCTATCAAAAGATTGACTCGGAAT
TTGTGGATTATCTGAAGAAGTCCTTTGCCATGAGCAAGGCCGAAAGTCTTCAAAAGGGGCTCAAGCACTTGGCCCAGTTG
ATTTTGAATGTTTTGGTCTTGTGGATGGGAGCTCATTTGGTCATGAAGCAAGAATTGAGTTTGGGTCAGCTGATTACCTA
CAATACTCTCCTTGTTTATTTCACAGGGCCTCTAGAGAATTTGATCAACCTCCAAACCAAACTTCAAGCCGCCCGAGTGG
CCAATACCCGTCTGAATGAAGTCTATCTGATAGACTCTGAGTTCGCAGAGAAGAAGCCCCTTCAAGAGCGTGAGGCTCTC
GATGGTGATCTGGTTTTTGAGGGAGTAGACTACAAGTACGGTTTTGGGGCCAATGTTCTAACAGATATTAACTTAAGGAT
CAAAAAAGGGAGCAAGGTGAGCTTTGTCGGTATTTCAGGCTCTGGAAAAACAACGCTAGCAAAGATGATGGTGAATTTCT
ACCAACCCCATAAAGGAACGATTCGTCTGGGAGGAAGGGATATCCAGCAAGTGGATAAAACCTTGCTCCGCCAGCAAATC
AATTATTTGCCCCAGCAGCCCTATGTCTTTAATGGCACGATCTTAGAGAACTTGTTACTAGGAGCGCGGGAAGGAACGAG
TCAGGAAGATATCTTGCGCGCTGTTGAAATCGCAGGAATTCGAGAAGATATTGAACGCATGCCCCTCAATTACCAAACGG
AATTAACAACGGATGGTATGGGAATTTCTGGTGGACAACGGCAGCGGATTGCTTTGGCGCGTGCTTTATTAACGGACGCT
CCGATTCTGATTCTGGATGAAGCGACCAGCAGCCTAGATATCTTGACGGAGAAGAAAATTGTGGACCGCTTGATGGCCTT
AGATAAGACCATTATCTTTATCGCCCATCGGTTAACGATTGCAGAACGGTCTGAAAAAGTCTTCCTCATGGACCAAGGTC
GTCTTATGGAAGAAGGAAGCCATGAAGAACTACTGAAAAAGAATGGCTATTACAGCCATTTGGTTACTTGTTAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(500-650)

Peptidase C39 family (Peptidase_C39)

(6-142)

ABC transporter transmembrane region (ABC_membrane)

(171-438)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

76.848

100

0.768
  comA Streptococcus mitis NCTC 12261

75.035

100

0.75
  comA Streptococcus pneumoniae Rx1

74.895

100

0.749
  comA Streptococcus pneumoniae D39

74.895

100

0.749
  comA Streptococcus pneumoniae R6

74.895

100

0.749
  comA Streptococcus mitis SK321

74.895

100

0.749
  comA Streptococcus pneumoniae TIGR4

74.477

100

0.745
  comA/nlmT Streptococcus mutans UA159

63.497

99.721

0.633