Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   KX728_RS09115 Genome accession   NZ_CP079724
Coordinates   1887954..1889252 (-) Length   432 a.a.
NCBI ID   WP_215804215.1    Uniprot ID   -
Organism   Streptococcus oralis strain 34     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1882954..1894252
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KX728_RS09095 (KX728_09090) - 1883288..1885261 (-) 1974 WP_000739974.1 DHH family phosphoesterase -
  KX728_RS09100 (KX728_09095) - 1885407..1886585 (-) 1179 WP_009013605.1 acetyl-CoA C-acetyltransferase -
  KX728_RS09105 (KX728_09100) hpf 1886667..1887215 (-) 549 WP_000599111.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  KX728_RS09110 (KX728_09105) comFC/cflB 1887295..1887957 (-) 663 WP_215804216.1 ComF family protein Machinery gene
  KX728_RS09115 (KX728_09110) comFA/cflA 1887954..1889252 (-) 1299 WP_215804215.1 DEAD/DEAH box helicase Machinery gene
  KX728_RS09120 (KX728_09115) - 1889309..1889944 (+) 636 WP_215804214.1 YigZ family protein -
  KX728_RS09125 (KX728_09120) - 1889960..1890403 (+) 444 WP_215804213.1 PH domain-containing protein -
  KX728_RS09130 (KX728_09125) cysK 1890500..1891426 (+) 927 WP_215804212.1 cysteine synthase A -
  KX728_RS09135 (KX728_09130) tsf 1891530..1892570 (-) 1041 WP_215804211.1 translation elongation factor Ts -
  KX728_RS09140 (KX728_09135) rpsB 1892649..1893428 (-) 780 WP_000268475.1 30S ribosomal protein S2 -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49595.44 Da        Isoelectric Point: 8.3637

>NTDB_id=589009 KX728_RS09115 WP_215804215.1 1887954..1889252(-) (comFA/cflA) [Streptococcus oralis strain 34]
MKVNPNYLGRLFTEKELTEEERQVAVKLPAMRKEKGKLFCQRCNSTILEEWYLPIGAYYCRECLLMKRVRSDQALYYFSQ
EDFPKQDVLKWRGQLTPFQEKVSEGLIRAVEKKEPTLVHAVTGAGKTEMIYQVVAKVIDDGGAVCLASPRIDVCLELYKR
LQNDFACEIALLHGESEPYFRTPLVVATTHQLLKFYHAFDLLIVDEVDAFPYVDNSALYYAVNQCVKEEGVRIFLTATST
DELDKKVRTGELKRLSLPRRFHGNPLIVPKPVWLSDFNRYIEKSQLSSKLKTYIEKQRRTGYPLLIFTSEIKKGEKLKEV
LQEQFPNENIGFVSSVTENRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGELLFFHDGLNVSIKKAIKEIKQMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=589009 KX728_RS09115 WP_215804215.1 1887954..1889252(-) (comFA/cflA) [Streptococcus oralis strain 34]
ATGAAAGTAAATCCAAATTACCTCGGTCGCTTGTTTACTGAGAAAGAATTAACTGAAGAAGAACGACAGGTAGCAGTGAA
ACTGCCAGCAATGAGAAAAGAGAAGGGGAAACTGTTTTGTCAACGTTGTAATAGTACGATTCTAGAAGAATGGTATTTGC
CTATTGGTGCCTACTATTGTAGGGAGTGTTTGCTGATGAAGCGAGTCAGGAGTGATCAAGCCTTATACTATTTTTCGCAG
GAAGATTTTCCAAAGCAAGATGTTCTCAAATGGCGTGGTCAGTTAACCCCTTTTCAGGAAAAGGTATCAGAGGGGTTGAT
TCGAGCAGTCGAAAAGAAAGAACCGACTTTAGTTCATGCTGTGACAGGTGCTGGAAAGACAGAGATGATCTATCAAGTTG
TAGCTAAAGTGATTGATGATGGTGGTGCAGTTTGTTTGGCCAGTCCTCGAATAGATGTTTGCTTGGAGTTGTATAAGCGA
CTGCAGAATGACTTTGCTTGTGAGATAGCACTACTTCATGGTGAGTCAGAACCCTATTTTCGAACACCACTAGTTGTTGC
AACGACTCATCAGCTGTTAAAATTTTATCATGCTTTTGATTTGCTAATAGTGGATGAAGTAGATGCCTTTCCTTATGTTG
ACAACTCTGCTCTTTACTATGCTGTAAACCAATGTGTAAAGGAGGAGGGGGTAAGGATATTTCTTACAGCGACTTCTACA
GATGAGTTAGATAAGAAGGTTCGCACTGGAGAATTAAAACGATTGAGCTTGCCAAGACGATTTCATGGAAATCCATTGAT
TGTTCCAAAGCCAGTTTGGTTATCAGACTTTAATCGCTATATAGAAAAGAGTCAGTTGTCATCCAAGTTAAAGACCTACA
TTGAGAAACAGAGAAGAACAGGTTATCCATTGCTAATTTTTACATCAGAGATTAAGAAAGGCGAAAAACTAAAAGAAGTC
TTGCAGGAACAGTTTCCAAATGAGAACATCGGCTTTGTGTCCTCTGTCACAGAAAATCGATTAGAGCAGGTACAAGCTTT
TCGAGATGGAGAGTTGACAATCCTTATTAGTACAACAATTTTGGAGCGTGGGGTCACCTTCCCTTGTGTGGATGTTTTTG
TTGTAGAAGCTAATCATCGTCTCTTTACCAAGTCTAGCTTGATTCAGATTGGAGGGCGAGTTGGGCGCAGTATGGATAGA
CCGACTGGTGAATTGCTCTTCTTTCATGATGGATTAAATGTTTCCATTAAAAAAGCAATCAAGGAAATTAAGCAGATGAA
CAAGGAGGCAGGCTTATGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-213)

Helicase conserved C-terminal domain (Helicase_C)

(291-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

89.583

100

0.896
  comFA/cflA Streptococcus pneumoniae Rx1

88.657

100

0.887
  comFA/cflA Streptococcus pneumoniae D39

88.657

100

0.887
  comFA/cflA Streptococcus pneumoniae R6

88.657

100

0.887
  comFA/cflA Streptococcus mitis SK321

88.426

100

0.884
  comFA/cflA Streptococcus pneumoniae TIGR4

88.426

100

0.884
  comFA Lactococcus lactis subsp. cremoris KW2

50.856

94.676

0.481
  comFA Latilactobacillus sakei subsp. sakei 23K

38.269

100

0.389