Detailed information NTG0587525

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: KV188_RS06160
• Genome accession: NZ_CP078508
• Coordinates: 1284194..1284850 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae serovar 8 str. 405
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 1279194..1289850

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KV188_RS06140 (KV188_06140)	nanA	1279566..1280444 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
KV188_RS06145 (KV188_06145)	nagB	1280494..1281297 (+)	804	WP_218633941.1	glucosamine-6-phosphate deaminase	-
KV188_RS06150 (KV188_06150)	nagA	1281349..1282494 (+)	1146	WP_218633942.1	N-acetylglucosamine-6-phosphate deacetylase	-
KV188_RS06155 (KV188_06155)	fumC	1282645..1284039 (-)	1395	WP_005605803.1	class II fumarate hydratase	-
KV188_RS06160 (KV188_06160)	sxy/tfoX	1284194..1284850 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
KV188_RS06165 (KV188_06165)	rpsJ	1285258..1285569 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
KV188_RS06170 (KV188_06170)	rplC	1285595..1286221 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
KV188_RS06175 (KV188_06175)	rplD	1286237..1286839 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
KV188_RS06180 (KV188_06180)	rplW	1286836..1287141 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
KV188_RS06185 (KV188_06185)	rplB	1287162..1287983 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
KV188_RS06190 (KV188_06190)	rpsS	1288011..1288286 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
KV188_RS06195 (KV188_06195)	rplV	1288297..1288629 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
KV188_RS06200 (KV188_06200)	rpsC	1288648..1289355 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
KV188_RS06205 (KV188_06205)	rplP	1289369..1289779 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=587525 KV188_RS06160 WP_005609196.1 1284194..1284850(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae serovar 8 str. 405]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=587525 KV188_RS06160 WP_005609196.1 1284194..1284850(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae serovar 8 str. 405]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376