Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   KVY09_RS04690 Genome accession   NZ_CP078159
Coordinates   953141..953770 (+) Length   209 a.a.
NCBI ID   WP_037551137.1    Uniprot ID   -
Organism   Staphylococcus haemolyticus strain NY5     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 948141..958770
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KVY09_RS13005 - 948846..948971 (-) 126 WP_256262273.1 hypothetical protein -
  KVY09_RS04665 (KVY09_04665) - 948984..949571 (-) 588 WP_256262274.1 SDR family NAD(P)-dependent oxidoreductase -
  KVY09_RS13010 - 949568..949705 (-) 138 WP_256262275.1 SDR family NAD(P)-dependent oxidoreductase -
  KVY09_RS04670 (KVY09_04670) - 949777..950782 (-) 1006 Protein_934 HoxN/HupN/NixA family nickel/cobalt transporter -
  KVY09_RS04675 (KVY09_04675) - 950996..951382 (+) 387 WP_053025474.1 hypothetical protein -
  KVY09_RS04680 (KVY09_04680) liaF 951407..952108 (+) 702 WP_053025472.1 cell wall-active antibiotics response protein LiaF -
  KVY09_RS04685 (KVY09_04685) vraS 952105..953151 (+) 1047 WP_053025471.1 sensor histidine kinase Regulator
  KVY09_RS04690 (KVY09_04690) vraR 953141..953770 (+) 630 WP_037551137.1 two-component system response regulator VraR Regulator
  KVY09_RS04695 (KVY09_04695) - 953833..955044 (-) 1212 WP_053025467.1 YihY/virulence factor BrkB family protein -
  KVY09_RS04700 (KVY09_04700) - 955243..955527 (-) 285 WP_053025464.1 YtxH domain-containing protein -
  KVY09_RS04705 (KVY09_04705) - 955512..955997 (-) 486 WP_070441564.1 low molecular weight protein-tyrosine-phosphatase -
  KVY09_RS04710 (KVY09_04710) - 956139..956347 (+) 209 Protein_942 DUF1128 domain-containing protein -
  KVY09_RS04715 (KVY09_04715) - 956361..957608 (+) 1248 WP_070441567.1 aminopeptidase -
  KVY09_RS04720 (KVY09_04720) - 957641..958174 (+) 534 WP_011275382.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23591.23 Da        Isoelectric Point: 5.0058

>NTDB_id=587409 KVY09_RS04690 WP_037551137.1 953141..953770(+) (vraR) [Staphylococcus haemolyticus strain NY5]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEIVGEGESGKDAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIADAVRKTYNGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=587409 KVY09_RS04690 WP_037551137.1 953141..953770(+) (vraR) [Staphylococcus haemolyticus strain NY5]
ATGACGATTAAAGTTTTGTTCGTTGATGACCATGAAATGGTTAGAATTGGGATATCAAGTTATCTATCAACACAATCTGA
CATTGAGATAGTTGGAGAAGGGGAATCTGGTAAAGATGCCATTGCAAAAGCTCATGAATTAAAACCTGATTTAATTCTTA
TGGATTTATTAATGGATGACATGGATGGCGTTGAAGCAACTACTCAAATCAAAAAAGATTTGCCACATATTAAAGTTGTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATAGAGCATTAGATGCTGGTGTAGATAGCTATATTTTAAAAACGAC
TAGTGCTAGTGATATAGCCGACGCAGTACGCAAAACTTATAATGGTGAATCTGTATTTGAACCTGAAGTTTTAGTTAAGA
TGCGTAACAGGATGAAGAAACGTGCAGAATTATATGAAATGCTGACTGAGCGTGAAATGGAAATTTTATTATTAATTGCA
AAAGGGTATTCAAATCAAGAAATAGCGAGTGCTTCTCATATTACAATTAAAACCGTTAAAACTCATGTAAGCAATATATT
GAGTAAATTAGAAGTACAAGATAGAACACAAGCCGTAATTTATGCATTCCAACATAATTTGATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.694

100

0.957
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.364