Detailed information NTG0586275

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: KV238_RS08415
• Genome accession: NZ_CP078012
• Coordinates: 1731231..1731968 (+)
• Length: 245 a.a.
• NCBI ID: WP_230923518.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ_18-036
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1726231..1736968

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KV238_RS08385 (KV238_08370)	-	1726685..1727590 (-)	906	WP_230923516.1	diacylglycerol/lipid kinase family protein	-
KV238_RS08390 (KV238_08375)	trhA	1727700..1728350 (-)	651	WP_042670617.1	PAQR family membrane homeostasis protein TrhA	-
KV238_RS08395 (KV238_08380)	-	1728334..1728789 (-)	456	WP_014622841.1	DUF1836 domain-containing protein	-
KV238_RS08400 (KV238_08385)	-	1729049..1729804 (+)	756	WP_230923517.1	class I SAM-dependent methyltransferase	-
KV238_RS08405 (KV238_08390)	-	1729832..1730170 (+)	339	WP_014622843.1	cupin domain-containing protein	-
KV238_RS08410 (KV238_08395)	-	1730172..1730477 (+)	306	WP_043052134.1	AraC family ligand binding domain-containing protein	-
KV238_RS08415 (KV238_08400)	comE/blpR	1731231..1731968 (+)	738	WP_230923518.1	response regulator transcription factor	Regulator
KV238_RS08420 (KV238_08405)	-	1732341..1732541 (+)	201	WP_012679509.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
KV238_RS08425 (KV238_08410)	-	1732608..1733462 (+)	855	WP_024273179.1	ABC transporter ATP-binding protein	-
KV238_RS08430 (KV238_08415)	-	1733468..1734631 (+)	1164	WP_024273178.1	ABC transporter permease subunit	-
KV238_RS08435 (KV238_08420)	-	1734893..1735123 (+)	231	WP_043038961.1	Blp family class II bacteriocin	-
KV238_RS08440 (KV238_08425)	-	1735916..1736770 (+)	855	WP_230923519.1	thioredoxin family protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28832.20 Da
• Isoelectric Point: 8.2679

>NTDB_id=586275 KV238_RS08415 WP_230923518.1 1731231..1731968(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHRLILHSQNGRIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKLKALEAS
IKALH

Nucleotide

• Length: 738 bp

>NTDB_id=586275 KV238_RS08415 WP_230923518.1 1731231..1731968(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAACAGTTTAGGCTTGAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACTTGTGATCGTTTTGAAGTTTATGGAAAGCCCTACCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATAGTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATCAGAAAGCGTGAC
CCTTATGCCCTCATTGTTTTTGTCACGACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATTGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATCGAGACCTCTAGTACTCCTCACAGGTTGATTTTGCATTCTCAAAACGGGCGAATAGAATTTTATGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATTCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAACGGGCAGTCTTGCATGGTTTCAAGACTAAAACTGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (18-122)

• LytTr DNA-binding domain (LytTR) (151-240)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	53.306	98.776	0.527
comE/comE1	Streptococcus equinus JB1	46.281	98.776	0.457
comE/comE2	Streptococcus equinus JB1	37.705	99.592	0.376