Detailed information NTG0585667

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: KVP03_RS07610
• Genome accession: NZ_CP077959
• Coordinates: 1607017..1607754 (-)
• Length: 245 a.a.
• NCBI ID: WP_043040551.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ_14-145
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1602017..1612754

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KVP03_RS10595	-	1602217..1602348 (-)	132	WP_228269170.1	LPXTG cell wall anchor domain-containing protein	-
KVP03_RS07585 (KVP03_07570)	-	1602389..1603069 (-)	681	WP_228269169.1	thioredoxin family protein	-
KVP03_RS07590 (KVP03_07575)	-	1603862..1604092 (-)	231	WP_111692439.1	Blp family class II bacteriocin	-
KVP03_RS07595 (KVP03_07580)	-	1604354..1605517 (-)	1164	WP_014622845.1	ABC transporter permease subunit	-
KVP03_RS07600 (KVP03_07585)	-	1605523..1606377 (-)	855	WP_012515593.1	ABC transporter ATP-binding protein	-
KVP03_RS07605 (KVP03_07590)	-	1606444..1606644 (-)	201	WP_042670621.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
KVP03_RS07610 (KVP03_07595)	comE/blpR	1607017..1607754 (-)	738	WP_043040551.1	response regulator transcription factor	Regulator
KVP03_RS07615 (KVP03_07600)	-	1608504..1608809 (-)	306	WP_111692436.1	AraC family ligand binding domain-containing protein	-
KVP03_RS07620 (KVP03_07605)	-	1608811..1609149 (-)	339	WP_014622843.1	cupin domain-containing protein	-
KVP03_RS07625 (KVP03_07610)	-	1609177..1609932 (-)	756	WP_043030786.1	class I SAM-dependent methyltransferase	-
KVP03_RS07630 (KVP03_07615)	-	1610193..1610648 (+)	456	WP_012515587.1	DUF1836 domain-containing protein	-
KVP03_RS07635 (KVP03_07620)	trhA	1610632..1611282 (+)	651	WP_012515586.1	PAQR family membrane homeostasis protein TrhA	-
KVP03_RS07640 (KVP03_07625)	-	1611392..1612297 (+)	906	WP_043025804.1	diacylglycerol/lipid kinase family protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28930.36 Da
• Isoelectric Point: 7.8609

>NTDB_id=585667 KVP03_RS07610 WP_043040551.1 1607017..1607754(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPHQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHKLILYSQNERIEFYGFLSEVLKQDPRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
IKALY

Nucleotide

• Length: 738 bp

>NTDB_id=585667 KVP03_RS07610 WP_043040551.1 1607017..1607754(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAACAGTTTAGGCTTGAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACGTGTGATCGTTTTGAAGTTTATGGAAAGCCCCATCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATAGTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATTAGAAAGCGTGAC
CCTTACGCTCTCATTGTTTTTGTCACGACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATCGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACTCCTCACAAGTTGATTTTGTATTCTCAAAACGAGCGAATAGAATTTTATGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATCCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAATGGGCAGTCTTGCATGGTTTCAAGACTAAAAATGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGTATTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-240)

• Response regulator receiver domain (Response_reg) (18-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.132	98.776	0.535
comE/comE1	Streptococcus equinus JB1	45.041	98.776	0.445
comE/comE2	Streptococcus equinus JB1	36.885	99.592	0.367