Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   KVP03_RS05555 Genome accession   NZ_CP077959
Coordinates   1154763..1156115 (+) Length   450 a.a.
NCBI ID   WP_014623188.1    Uniprot ID   A0A6M1KZW6
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ_14-145     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1149763..1161115
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KVP03_RS05530 (KVP03_05510) - 1149895..1150434 (+) 540 WP_230922954.1 hypothetical protein -
  KVP03_RS05535 (KVP03_05515) - 1150431..1151546 (+) 1116 WP_230922955.1 acetyl-CoA C-acyltransferase -
  KVP03_RS05540 (KVP03_05520) - 1151536..1152798 (+) 1263 WP_230922956.1 AMP-binding protein -
  KVP03_RS05545 (KVP03_05525) - 1152844..1153863 (+) 1020 WP_230922957.1 DUF3114 domain-containing protein -
  KVP03_RS05550 (KVP03_05530) vicR 1154060..1154770 (+) 711 WP_012677635.1 response regulator YycF Regulator
  KVP03_RS05555 (KVP03_05535) vicK 1154763..1156115 (+) 1353 WP_014623188.1 cell wall metabolism sensor histidine kinase VicK Regulator
  KVP03_RS05560 (KVP03_05540) vicX 1156119..1156928 (+) 810 WP_021320992.1 MBL fold metallo-hydrolase Regulator
  KVP03_RS05565 (KVP03_05545) - 1157808..1159322 (+) 1515 WP_230922958.1 helix-turn-helix domain-containing protein -
  KVP03_RS05570 (KVP03_05550) rnc 1159581..1160273 (+) 693 WP_043053292.1 ribonuclease III -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51527.91 Da        Isoelectric Point: 5.5557

>NTDB_id=585660 KVP03_RS05555 WP_014623188.1 1154763..1156115(+) (vicK) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLMSHKIRDLINGRYTDTINEKADIELMELSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVTQLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITS
IWLEIDNDKMTQVIENILNNAIKYSPDGGKIVVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=585660 KVP03_RS05555 WP_014623188.1 1154763..1156115(+) (vicK) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
ATGACTAAGGACATCATTGGAAACCTTTCTGCATTTGAGCTAGCCATACTCTTATTGCTTGTTTTTGTTGCTTTTTATTT
CATTCATTTAGCCATTCGTGATTATCGCAATGCTCGGATCATTCGTCTGATGAGCCACAAGATAAGAGATTTGATCAATG
GTCGCTATACGGACACGATCAATGAAAAGGCTGATATTGAATTGATGGAGCTGTCTGAGCAGCTCAATGACCTATCAGAT
GTTTTTCGTCTGACTCATGAAAACCTTGCTCAAGAAAAAAATCGTCTTGCTAGTATTTTGGCTTATATGACAGATGGGGT
CCTTGCGACCAATCGTTCCGGCAAGATTATCATGATTAATGAGACTGCTCAAAAGCAGCTCAATTTAAATCGCGAGCAGG
CCTTGGAAAAAAACATTACAGATTTATTAGACAGTGACTCCCCTTATACCTACCGAGAGCTGGTCTCAAAAACACCGATT
GTGACTTTAAACCGTCGTAATGATACAGGAGAATTTGTTTCCCTGCGGCTGCGCTTTGCGCTTAATAGGCGAGAGAGCGG
CTTTATTTCAGGTCTGGTTGTTGTGCTTCATGACACGACTGAGCAGGAAAAGGAAGAGCGCGAGCGCAGACTCTTTGTTT
CAAATGTTAGCCATGAGCTGCGGACACCTTTGACCTCTGTCAAGTCATACCTAGAGGCTCTAGATGAGGGCGCGCTAAAG
GAGGACATCGCTCCAAGCTTTATAAAGGTCTCACTGGACGAAACCAATCGCATGATGCGCATGATTTCAGATTTGCTCAA
TCTATCAAGAATTGATAATCATGTGACACAGTTGTCTGTTGAAATGACCAACTTTACAGCCTTTATGACCTCTATCTTAA
ACCGCTTTGATTTGGTGAAAAATCAGCACACAAGCACAGGAAAATCCTATGAAATTGTCAGAGATTACCCTATTACCTCT
ATTTGGCTAGAAATTGATAACGATAAAATGACGCAGGTCATTGAAAATATTTTAAACAATGCCATCAAATATTCACCCGA
TGGCGGAAAAATTGTCGTCAACATGAAAACAACAGATACCCAGCTAATCATTTCGATTTCTGATGAGGGCTTGGGCATTC
CAAAAAAGGACCTGCCTTTGATTTTTGACCGTTTTTACCGAGTGGATAAGGCTAGAAGTCGGGCTCAAGGAGGAACTGGT
CTAGGCTTAGCGATTGCTAAAGAAATTATTAAGCAGCACCGCGGCTTTATCTGGGCTAAGAGTGACTATGGCAAGGGGTC
AACCTTTACCATTGTGTTACCTTACGAAAAGGATGCTGCTATCTATGATGAATGGGAGGATGATATTGATTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6M1KZW6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92

0.678
  micB Streptococcus pneumoniae Cp1015

66.824

94.444

0.631