Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MYL26_RS25040 Genome accession   NZ_CP095823
Coordinates   5097290..5097880 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain STE15     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 5092290..5102880
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MYL26_RS25025 (MYL26_24900) uhpT 5092812..5094203 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  MYL26_RS25030 (MYL26_24905) uhpC 5094459..5095778 (-) 1320 WP_001696326.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  MYL26_RS25035 (MYL26_24910) uhpB 5095788..5097290 (-) 1503 WP_001318135.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  MYL26_RS25040 (MYL26_24915) letA 5097290..5097880 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  MYL26_RS25045 (MYL26_24920) ilvN 5097953..5098243 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  MYL26_RS25050 (MYL26_24925) ilvB 5098247..5099935 (-) 1689 WP_000168476.1 acetolactate synthase large subunit -
  MYL26_RS25055 (MYL26_24930) ivbL 5100041..5100139 (-) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  MYL26_RS25060 (MYL26_24935) tisB 5100703..5100792 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  MYL26_RS25065 (MYL26_24940) ysdE 5100916..5100990 (-) 75 WP_211180519.1 protein YsdE -
  MYL26_RS25070 (MYL26_24945) emrD 5101072..5102256 (+) 1185 WP_001696327.1 multidrug efflux MFS transporter EmrD -
  MYL26_RS25075 (MYL26_24950) yidF 5102264..5102761 (-) 498 WP_000148034.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=585090 MYL26_RS25040 WP_000633668.1 5097290..5097880(-) (letA) [Escherichia coli strain STE15]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=585090 MYL26_RS25040 WP_000633668.1 5097290..5097880(-) (letA) [Escherichia coli strain STE15]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCCGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGTATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378