Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   MYL51_RS20945 Genome accession   NZ_CP095816
Coordinates   4279616..4280275 (+) Length   219 a.a.
NCBI ID   WP_001221478.1    Uniprot ID   B7UIT0
Organism   Escherichia coli strain FY10     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 4274616..4285275
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MYL51_RS20930 (MYL51_20875) ygiS 4276821..4278428 (-) 1608 WP_000288665.1 ABC transporter substrate-binding protein -
  MYL51_RS20935 (MYL51_20880) ygiV 4278537..4279019 (-) 483 WP_000183493.1 GyrI-like domain-containing protein -
  MYL51_RS20940 (MYL51_20885) ygiW 4279072..4279464 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  MYL51_RS20945 (MYL51_20890) ciaR 4279616..4280275 (+) 660 WP_001221478.1 quorum sensing response regulator transcription factor QseB Regulator
  MYL51_RS20950 (MYL51_20895) qseC 4280272..4281621 (+) 1350 WP_000673349.1 quorum sensing histidine kinase QseC -
  MYL51_RS20955 (MYL51_20900) mdaB 4281731..4282312 (+) 582 WP_000065421.1 NADPH:quinone oxidoreductase MdaB -
  MYL51_RS20960 (MYL51_20905) ygiN 4282343..4282657 (+) 315 WP_000633738.1 putative quinol monooxygenase -
  MYL51_RS20965 (MYL51_20910) - 4282702..4283589 (-) 888 WP_000614959.1 MurR/RpiR family transcriptional regulator -
  MYL51_RS20970 (MYL51_20915) - 4283586..4284533 (-) 948 WP_001318046.1 iron-siderophore ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24701.65 Da        Isoelectric Point: 6.9850

>NTDB_id=584906 MYL51_RS20945 WP_001221478.1 4279616..4280275(+) (ciaR) [Escherichia coli strain FY10]
MRILLIEDDMLIGDGIKTGLSKMGFSIDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=584906 MYL51_RS20945 WP_001221478.1 4279616..4280275(+) (ciaR) [Escherichia coli strain FY10]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCAT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTATATAGCGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGCAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACGCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B7UIT0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365