Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   MYL30_RS03950 Genome accession   NZ_CP095795
Coordinates   802514..803173 (-) Length   219 a.a.
NCBI ID   WP_001221478.1    Uniprot ID   B7UIT0
Organism   Escherichia coli strain CT265     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 797514..808173
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MYL30_RS03925 (MYL30_03915) - 798256..799203 (+) 948 WP_001318046.1 iron-siderophore ABC transporter substrate-binding protein -
  MYL30_RS03930 (MYL30_03920) - 799200..800087 (+) 888 WP_000614959.1 MurR/RpiR family transcriptional regulator -
  MYL30_RS03935 (MYL30_03925) ygiN 800132..800446 (-) 315 WP_000633738.1 putative quinol monooxygenase -
  MYL30_RS03940 (MYL30_03930) mdaB 800477..801058 (-) 582 WP_000065421.1 NADPH:quinone oxidoreductase MdaB -
  MYL30_RS03945 (MYL30_03935) qseC 801168..802517 (-) 1350 WP_000673349.1 quorum sensing histidine kinase QseC -
  MYL30_RS03950 (MYL30_03940) ciaR 802514..803173 (-) 660 WP_001221478.1 quorum sensing response regulator transcription factor QseB Regulator
  MYL30_RS03955 (MYL30_03945) ygiW 803325..803717 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  MYL30_RS03960 (MYL30_03950) ygiV 803770..804252 (+) 483 WP_000183493.1 GyrI-like domain-containing protein -
  MYL30_RS03965 (MYL30_03955) ygiS 804361..805968 (+) 1608 WP_000288665.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24701.65 Da        Isoelectric Point: 6.9850

>NTDB_id=584518 MYL30_RS03950 WP_001221478.1 802514..803173(-) (ciaR) [Escherichia coli strain CT265]
MRILLIEDDMLIGDGIKTGLSKMGFSIDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=584518 MYL30_RS03950 WP_001221478.1 802514..803173(-) (ciaR) [Escherichia coli strain CT265]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCAT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTATATAGCGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGCAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACGCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B7UIT0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365