Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MU520_RS08045 Genome accession   NZ_CP095463
Coordinates   1641896..1642537 (-) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain TJS56     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1636896..1647537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MU520_RS08020 comFA/cflA 1637050..1638342 (-) 1293 WP_012774986.1 DEAD/DEAH box helicase Machinery gene
  MU520_RS08025 - 1638399..1639031 (+) 633 WP_014636235.1 YigZ family protein -
  MU520_RS08030 cysK 1639121..1640047 (+) 927 WP_012774985.1 cysteine synthase A -
  MU520_RS08035 - 1640073..1640444 (-) 372 WP_011921997.1 S1 RNA-binding domain-containing protein -
  MU520_RS08040 - 1640446..1641846 (-) 1401 WP_011921996.1 Cof-type HAD-IIB family hydrolase -
  MU520_RS08045 vraR 1641896..1642537 (-) 642 WP_002937025.1 response regulator transcription factor Regulator
  MU520_RS08050 - 1642509..1643525 (-) 1017 WP_002937028.1 sensor histidine kinase -
  MU520_RS08055 liaF 1643522..1644181 (-) 660 WP_223375661.1 cell wall-active antibiotics response protein LiaF -
  MU520_RS08060 stkP 1644638..1646632 (-) 1995 WP_011921992.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  MU520_RS08065 - 1646632..1647369 (-) 738 WP_012774983.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=583039 MU520_RS08045 WP_002937025.1 1641896..1642537(-) (vraR) [Streptococcus suis strain TJS56]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=583039 MU520_RS08045 WP_002937025.1 1641896..1642537(-) (vraR) [Streptococcus suis strain TJS56]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGCCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCGTTAGAGGTTAAACCTGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACTCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTATCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATATCCTTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413