Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   MU414_RS03775 Genome accession   NZ_CP095137
Coordinates   763849..764508 (-) Length   219 a.a.
NCBI ID   WP_001546136.1    Uniprot ID   -
Organism   Escherichia coli strain Iso00225     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 758849..769508
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MU414_RS03745 ygiN 759750..760064 (-) 315 WP_000633738.1 putative quinol monooxygenase -
  MU414_RS03750 mdaB 760095..760676 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  MU414_RS03755 - 760926..761405 (+) 480 WP_000065331.1 Hcp family type VI secretion system effector -
  MU414_RS03760 - 761408..762118 (+) 711 WP_000834022.1 hypothetical protein -
  MU414_RS03765 ygiZ 762125..762457 (+) 333 WP_000914696.1 DUF2645 family protein -
  MU414_RS03770 qseC 762503..763852 (-) 1350 WP_001546137.1 quorum sensing histidine kinase QseC -
  MU414_RS03775 ciaR 763849..764508 (-) 660 WP_001546136.1 quorum sensing response regulator transcription factor QseB Regulator
  MU414_RS03780 ygiW 764660..765052 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  MU414_RS03785 ygiV 765105..765587 (+) 483 WP_000183493.1 GyrI-like domain-containing protein -
  MU414_RS03790 ygiS 765696..767303 (+) 1608 WP_001468194.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24615.56 Da        Isoelectric Point: 7.4216

>NTDB_id=582491 MU414_RS03775 WP_001546136.1 763849..764508(-) (ciaR) [Escherichia coli strain Iso00225]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWRGKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=582491 MU414_RS03775 WP_001546136.1 763849..764508(-) (ciaR) [Escherichia coli strain Iso00225]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAAGCGCTATATAGCGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGGAAAAGGTCAGCGTGAGCCTGTATTGATCCTGACTGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGCAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACGCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTTCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

37.885

100

0.393
  ciaR Streptococcus pneumoniae D39

37.885

100

0.393
  ciaR Streptococcus pneumoniae R6

37.885

100

0.393
  ciaR Streptococcus pneumoniae TIGR4

37.885

100

0.393
  ciaR Streptococcus mutans UA159

35.426

100

0.361