Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MU416_RS00175 Genome accession   NZ_CP095125
Coordinates   33004..33594 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain Iso00270     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 28004..38594
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MU416_RS00140 yidF 28119..28616 (+) 498 WP_000148061.1 radical SAM protein -
  MU416_RS00145 emrD 28624..29808 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  MU416_RS00150 ysdE 29890..29964 (+) 75 WP_211180519.1 protein YsdE -
  MU416_RS00155 tisB 30088..30177 (-) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  MU416_RS00160 ivbL 30742..30840 (+) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  MU416_RS00165 ilvB 30946..32634 (+) 1689 WP_000168475.1 acetolactate synthase large subunit -
  MU416_RS00170 ilvN 32638..32928 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  MU416_RS00175 letA 33004..33594 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  MU416_RS00180 uhpB 33594..35096 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  MU416_RS00185 uhpC 35106..36425 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  MU416_RS00190 uhpT 36563..37954 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=582397 MU416_RS00175 WP_000633668.1 33004..33594(+) (letA) [Escherichia coli strain Iso00270]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=582397 MU416_RS00175 WP_000633668.1 33004..33594(+) (letA) [Escherichia coli strain Iso00270]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378