Detailed information NTG0580378

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: I6L86_RS04695
• Genome accession: NZ_CP077259
• Coordinates: 1004918..1005928 (+)
• Length: 336 a.a.
• NCBI ID: WP_001090627.1
• Uniprot ID: I0SX71
• Organism: Streptococcus mitis strain FDAARGOS 1456
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 999918..1010928

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6L86_RS04670 (I6L86_04670)	folP	1000514..1001488 (+)	975	WP_000240964.1	dihydropteroate synthase	-
I6L86_RS04675 (I6L86_04675)	-	1001490..1002812 (+)	1323	WP_000658435.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-
I6L86_RS04680 (I6L86_04680)	folE	1002793..1003347 (+)	555	WP_000380931.1	GTP cyclohydrolase I FolE	-
I6L86_RS04685 (I6L86_04685)	folK	1003390..1004202 (+)	813	WP_000372493.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
I6L86_RS04690 (I6L86_04690)	-	1004363..1004680 (-)	318	WP_000886035.1	DUF960 domain-containing protein	-
I6L86_RS04695 (I6L86_04695)	ccpA	1004918..1005928 (+)	1011	WP_001090627.1	catabolite control protein A	Regulator
I6L86_RS04700 (I6L86_04700)	-	1005982..1006944 (-)	963	WP_001124765.1	asparaginase	-
I6L86_RS04705 (I6L86_04705)	-	1007010..1008401 (+)	1392	WP_078228369.1	Cof-type HAD-IIB family hydrolase	-
I6L86_RS04710 (I6L86_04710)	-	1008617..1009069 (-)	453	WP_000079148.1	universal stress protein	-
I6L86_RS04715 (I6L86_04715)	-	1009231..1009533 (+)	303	WP_000977176.1	hypothetical protein	-
I6L86_RS04720 (I6L86_04720)	-	1009690..1010904 (+)	1215	WP_000666474.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37169.19 Da
• Isoelectric Point: 5.3350

>NTDB_id=580378 I6L86_RS04695 WP_001090627.1 1004918..1005928(+) (ccpA) [Streptococcus mitis strain FDAARGOS 1456]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDDKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVTYLAKENERIAFVSGPLVDDINGKVRLVGYKEALKKAGISYSEGLVFESKYTYEDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEEFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=580378 I6L86_RS04695 WP_001090627.1 1004918..1005928(+) (ccpA) [Streptococcus mitis strain FDAARGOS 1456]
ATGAATACAGACGATACAGTAACGATTTATGATGTCGCCCGTGAAGCAGGAGTTTCAATGGCGACAGTTAGCCGTGTAGT
CAATGGCAATAAGAATGTAAAAGAGAATACTCGTAAAAAAGTGCTTGAGGTGATTGACCGTTTGGATTACCGTCCAAATG
CAGTGGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTGGTGATACCAAATATTACCAATGGTTATTTCTCA
ACGCTTGCCAAAGGGATTGATGATATTGCTGAAATGTACAAGTATAATATCGTTCTTGCTAATAGTGATGAGGATGATGA
TAAGGAAGTTTCAGTTGTCAATACCCTGTTTTCTAAGCAAGTGGATGGTATCATCTTTATGGGGTACCACTTGACTGAAA
AAATTCGTTCAGAGTTTTCTCGTTCTCGAACACCAGTTGTTCTTGCAGGAACTGTGGATGTAGAACACCAACTTCCAAGT
GTTAATATTGACTACAAACAAGCTACGATTGATGCAGTGACCTACCTTGCTAAAGAAAATGAGCGCATTGCTTTCGTAAG
CGGTCCACTAGTGGATGATATCAATGGTAAGGTTCGTTTGGTTGGCTACAAGGAAGCCTTGAAAAAAGCAGGTATTTCTT
ATAGCGAAGGATTGGTATTTGAGTCTAAATACACTTATGAAGATGGTTATGCCTTGGCAGAACGCTTGATTTCATCAAAC
GCAACTGCAGCAGTTGTAACAGGTGATGAGCTGGCAGCAGGTGTCTTGAACGGCCTTGCTGATAAGGGTGTATCAGTACC
AGAAGAATTTGAAATCATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACTATTGCCCAAC
CTCTTTATGACCTTGGGGCCATCAGTATGCGTATGTTGACCAAGATTATGCACAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTCGCTCAACACGAAAACGGAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: I0SX71

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	95.536	100	0.955
ccpA	Streptococcus gordonii str. Challis substr. CH1	89.521	99.405	0.89
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	58.006	98.512	0.571