Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   I6L84_RS07990 Genome accession   NZ_CP077224
Coordinates   1622494..1623795 (-) Length   433 a.a.
NCBI ID   WP_060552928.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS 1454     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1617494..1628795
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L84_RS07980 (I6L84_07980) raiA 1621205..1621747 (-) 543 WP_012000104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  I6L84_RS07985 (I6L84_07985) comFC/cflB 1621832..1622497 (-) 666 WP_012000103.1 ComF family protein Machinery gene
  I6L84_RS07990 (I6L84_07990) comFA/cflA 1622494..1623795 (-) 1302 WP_060552928.1 DEAD/DEAH box helicase Machinery gene
  I6L84_RS07995 (I6L84_07995) - 1623851..1624483 (+) 633 WP_060552929.1 YigZ family protein -
  I6L84_RS08000 (I6L84_08000) cysK 1624581..1625510 (+) 930 WP_008808600.1 cysteine synthase A -
  I6L84_RS08005 (I6L84_08005) - 1625547..1625933 (-) 387 WP_060552930.1 S1 RNA-binding domain-containing protein -
  I6L84_RS08010 (I6L84_08010) - 1625930..1627333 (-) 1404 WP_060552931.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  I6L84_RS08015 (I6L84_08015) - 1627421..1628053 (-) 633 WP_060552932.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49326.36 Da        Isoelectric Point: 8.6741

>NTDB_id=580048 I6L84_RS07990 WP_060552928.1 1622494..1623795(-) (comFA/cflA) [Streptococcus gordonii strain FDAARGOS 1454]
MLELQDCLGRIFTKEQLPTELLKIAQRLPSVFEKKGELFCSRCHSQIDKERNLLPIGAYYCRECILLGRVRSDEDLYYFS
QESFPIISSLKWLGQLTEYQERVSKGLLEGVQSKQDTLVHAVTGAGKTEMIYQVVARVLDQGGAVCIASPRIDVCLELYR
RLKGDFFCDISLLHGESDPYSRSPLVIATTHQLLKFYQAFDLLIVDEVDAFPYVDNPVLYHAVEQAVKNEGTTIFLTATS
TDELDKKVQKGILKRLSLPRRFHGNPLIIPQKVWLSDLNKDLKKAKLPAKLVKYLRKQRKTKFPLLIFASEIKKGQEIKQ
VLQKYFPEETVGFVASTTENRLEIVQDFRDKKISILVTTTILERGVTFPCVDVIVLEANHRLFTRSALVQIGGRVGRSME
RPTGDLLFFHDGTNIQIEKAINEIKAMNREAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=580048 I6L84_RS07990 WP_060552928.1 1622494..1623795(-) (comFA/cflA) [Streptococcus gordonii strain FDAARGOS 1454]
ATGTTAGAATTGCAAGATTGTCTCGGTCGAATTTTTACTAAAGAACAGTTACCTACTGAACTTTTGAAGATAGCTCAAAG
ACTACCATCAGTTTTTGAAAAAAAAGGAGAACTCTTTTGTTCTCGCTGCCACAGTCAAATTGATAAGGAAAGAAATTTAT
TACCAATTGGTGCATATTATTGTAGAGAATGCATTCTTCTAGGGAGAGTACGTAGTGACGAAGATCTTTATTATTTTTCT
CAAGAATCTTTTCCTATAATATCGAGTTTGAAATGGCTCGGCCAATTGACAGAATATCAGGAAAGAGTTTCTAAGGGATT
ACTTGAAGGAGTACAAAGTAAACAGGATACTTTAGTCCACGCTGTAACTGGAGCAGGAAAAACGGAAATGATCTATCAAG
TGGTTGCTCGGGTGTTAGATCAAGGAGGGGCTGTCTGTATAGCTAGTCCTCGGATAGATGTCTGTTTGGAACTGTACCGA
CGTTTAAAAGGAGATTTCTTCTGTGATATTTCCCTTTTGCATGGGGAGTCCGACCCCTATTCACGGAGTCCCCTAGTGAT
TGCAACAACTCATCAATTATTAAAATTTTACCAAGCATTTGATCTACTCATTGTTGACGAGGTGGATGCCTTCCCTTATG
TAGATAATCCTGTGCTTTATCATGCAGTCGAGCAAGCAGTTAAAAATGAAGGAACTACTATATTCTTGACCGCAACTTCA
ACAGATGAGCTTGATAAAAAAGTTCAAAAAGGAATTTTAAAAAGGTTAAGTTTGCCAAGACGCTTTCATGGAAATCCCTT
GATTATCCCACAAAAAGTATGGCTTTCTGATCTAAATAAAGACCTTAAAAAAGCTAAGCTACCAGCTAAGTTAGTCAAGT
ATTTGAGAAAACAAAGAAAAACAAAATTTCCACTCTTAATTTTTGCTTCGGAGATTAAGAAAGGACAAGAGATAAAGCAA
GTCTTACAGAAATATTTTCCAGAAGAAACTGTAGGCTTTGTAGCCTCTACAACGGAAAATAGATTAGAAATTGTGCAAGA
TTTTCGAGATAAAAAAATAAGTATACTAGTTACAACTACAATTTTAGAAAGAGGCGTTACTTTTCCCTGTGTAGATGTTA
TTGTTCTAGAAGCTAACCATCGTCTCTTTACAAGGAGTGCTTTAGTACAAATTGGCGGGCGAGTAGGAAGAAGTATGGAA
CGACCTACAGGTGACTTACTATTTTTTCATGATGGCACTAATATACAGATAGAAAAAGCAATCAATGAAATTAAAGCAAT
GAATAGAGAGGCTGGCTTATGA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(97-245)

Helicase conserved C-terminal domain (Helicase_C)

(289-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae TIGR4

69.393

98.845

0.686
  comFA/cflA Streptococcus pneumoniae Rx1

69.393

98.845

0.686
  comFA/cflA Streptococcus pneumoniae D39

69.393

98.845

0.686
  comFA/cflA Streptococcus pneumoniae R6

69.393

98.845

0.686
  comFA/cflA Streptococcus mitis NCTC 12261

69.484

98.383

0.684
  comFA/cflA Streptococcus mitis SK321

69.484

98.383

0.684
  comFA Lactococcus lactis subsp. cremoris KW2

53.807

90.993

0.49
  comFA Latilactobacillus sakei subsp. sakei 23K

39.767

99.307

0.395