Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   SPN032672_RS08820 Genome accession   NC_021003
Coordinates   1656413..1657150 (+) Length   245 a.a.
NCBI ID   WP_001219141.1    Uniprot ID   -
Organism   Streptococcus pneumoniae SPN032672     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1651413..1662150
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN032672_RS13355 - 1652343..1652582 (-) 240 WP_001813906.1 hypothetical protein -
  SPN032672_RS08790 - 1652744..1653031 (-) 288 WP_000777753.1 hypothetical protein -
  SPN032672_RS08795 - 1653041..1653451 (-) 411 WP_001278304.1 HIT family protein -
  SPN032672_RS08800 pptA 1653519..1654250 (+) 732 WP_000889923.1 ABC transporter ATP-binding protein Regulator
  SPN032672_RS08805 - 1654247..1655296 (+) 1050 WP_000653751.1 ABC transporter permease -
  SPN032672_RS08810 - 1655464..1655793 (-) 330 WP_000132572.1 hypothetical protein -
  SPN032672_RS08815 - 1656070..1656408 (+) 339 WP_000682133.1 LytTR family DNA-binding domain-containing protein -
  SPN032672_RS08820 comE/blpR 1656413..1657150 (+) 738 WP_001219141.1 response regulator transcription factor Regulator
  SPN032672_RS08825 - 1657164..1658504 (+) 1341 WP_001099892.1 sensor histidine kinase -
  SPN032672_RS08830 blpC 1658548..1658703 (-) 156 WP_000358811.1 quorum-sensing system pheromone BlpC -
  SPN032672_RS08835 - 1658760..1660121 (-) 1362 WP_001069071.1 bacteriocin secretion accessory protein -
  SPN032672_RS08840 comA/nlmT 1660132..1661622 (-) 1491 WP_001818755.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28752.87 Da        Isoelectric Point: 6.2366

>NTDB_id=57900 SPN032672_RS08820 WP_001219141.1 1656413..1657150(+) (comE/blpR) [Streptococcus pneumoniae SPN032672]
MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=57900 SPN032672_RS08820 WP_001219141.1 1656413..1657150(+) (comE/blpR) [Streptococcus pneumoniae SPN032672]
ATGAGAATATTTGTTTTAGAGGATGATTTTTCCCAACAGACTAGGATTGAAACGACGATTGAGAAACTCTTGAAGGAACA
TCATATCACTCCCAGCTCTTTTGAGGTATTTGGCAAGCCAGACCAACTGCTGGCAGAGGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAGGAGATGAAGGGTCTGGAAGTGGCTAGAAAGATTCGGGATCGGGAT
CCGTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTCTGGA
CTATATTGATAAGGCCCTTTCGGCAGAGGAGTTTGAATCTCGTATCGAGACAGCCCTCCTCTATGCCAATGGTCAAGACA
GTAAAAGTCTAGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCTCAATTCCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCCACAAGACCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTCTAGAGGA
GGTTCTCAAGCAGGAGCCTCGTCTCTTGCAGTGCCATCGCTCTTTTCTCATCAATCCTGCCAATGTGGTGCATTTAGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATTAATAACTTACACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.441

100

0.539
  comE/comE1 Streptococcus equinus JB1

43.038

96.735

0.416
  comE/comE2 Streptococcus equinus JB1

38.43

98.776

0.38

Multiple sequence alignment