Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MQV61_RS00150 Genome accession   NZ_CP094339
Coordinates   28553..29143 (+) Length   196 a.a.
NCBI ID   WP_001332271.1    Uniprot ID   A0A0H2Z4C4
Organism   Escherichia coli strain W224N     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 23553..34143
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MQV61_RS00115 yidG 23845..24207 (+) 363 WP_001113443.1 DUF202 domain-containing protein -
  MQV61_RS00120 yidF 24204..24701 (+) 498 WP_000148034.1 radical SAM protein -
  MQV61_RS00125 emrD 24709..25893 (-) 1185 WP_001332269.1 multidrug efflux MFS transporter EmrD -
  MQV61_RS00130 ysdE 25975..26049 (+) 75 WP_211180519.1 protein YsdE -
  MQV61_RS00135 ivbL 26294..26392 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  MQV61_RS00140 ilvB 26498..28186 (+) 1689 WP_000168473.1 acetolactate synthase large subunit -
  MQV61_RS00145 ilvN 28190..28480 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  MQV61_RS00150 letA 28553..29143 (+) 591 WP_001332271.1 transcriptional regulator UhpA Regulator
  MQV61_RS00155 uhpB 29143..30645 (+) 1503 WP_001332272.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  MQV61_RS00160 uhpC 30655..31974 (+) 1320 WP_001350834.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  MQV61_RS00165 uhpT 32112..33503 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20836.26 Da        Isoelectric Point: 5.6059

>NTDB_id=577401 MQV61_RS00150 WP_001332271.1 28553..29143(+) (letA) [Escherichia coli strain W224N]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGCGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=577401 MQV61_RS00150 WP_001332271.1 28553..29143(+) (letA) [Escherichia coli strain W224N]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGTGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCCGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCGCCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(136-191)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2Z4C4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378