Detailed information NTG0577263

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: MP387_RS08425
• Genome accession: NZ_CP094226
• Coordinates: 1726969..1729503 (-)
• Length: 844 a.a.
• NCBI ID: WP_242746306.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain 1648
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1721969..1734503

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MP387_RS08400 (MP387_08400)	ruvA	1722379..1722972 (-)	594	WP_242746285.1	Holliday junction branch migration protein RuvA	Machinery gene
MP387_RS08405 (MP387_08405)	-	1723132..1723629 (+)	498	WP_242748064.1	helix-turn-helix transcriptional regulator	-
MP387_RS08410 (MP387_08410)	hexB	1723770..1725719 (-)	1950	WP_242746288.1	DNA mismatch repair endonuclease MutL	Machinery gene
MP387_RS08415 (MP387_08415)	-	1726033..1726473 (+)	441	WP_242746292.1	LytTR family DNA-binding domain-containing protein	-
MP387_RS08420 (MP387_08420)	-	1726470..1726928 (+)	459	WP_242746304.1	DUF3021 domain-containing protein	-
MP387_RS08425 (MP387_08425)	hexA	1726969..1729503 (-)	2535	WP_242746306.1	DNA mismatch repair protein MutS	Machinery gene
MP387_RS08430 (MP387_08430)	argR	1729554..1730000 (-)	447	WP_242746308.1	arginine repressor	-
MP387_RS08435 (MP387_08435)	argS	1730155..1731846 (+)	1692	WP_242746310.1	arginine--tRNA ligase	-
MP387_RS08440 (MP387_08440)	-	1732184..1732429 (+)	246	WP_000084865.1	hypothetical protein	-
MP387_RS08445 (MP387_08445)	-	1732629..1733891 (+)	1263	WP_242746312.1	NRAMP family divalent metal transporter	-
MP387_RS08450 (MP387_08450)	nrdI	1733973..1734443 (-)	471	WP_242746314.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-

Sequence

Protein

• Length: 844 a.a.
• Molecular weight: 94669.14 Da
• Isoelectric Point: 4.8891

>NTDB_id=577263 MP387_RS08425 WP_242746306.1 1726969..1729503(-) (hexA) [Streptococcus oralis strain 1648]
MATEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAINAAQILEISLTSRNKNAENPIPMAGVPYHSAQQYIDVLI
EQGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVAVDRDGNQFGLAYMDLVTGDFYVTGLLDFTL
VCGEIRNLKAREVVLGYDLSEEEEQIFSCQMNLVLSYEKEGFEDIHLLDPRLAAVEQAAASKLLQYVHRTQMRELNHLKP
VIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLFWLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFF
ERSDLTDSLKGVYDIERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELESLISAAIAP
EAPHVITEGGIIRTGFDETLDKYRRVLREGTSWIAEIEAKERENSGISTLKIDYNKKDGYYFHVTNSQLGNVPAHFFRKA
TLKNSERFGTEELARIEGDMLEAREKSANLEYEIFMRIREEVSKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFG
EDSQIAIQKGRHAVVEKVMGAQTYIPNSIQMSEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQLGSYVPAESAHLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANNAISHATKDSLILFDELGRGTATYDGMALAQSIIEYIHKHIGAKTLFATHYHEL
TSLESSLEHLVNVHVATLEQDGQVTFLHKIEPGPADKSYGIHVAKIAGLPAELLARADKILTQLENQGTESPVPIRETSA
VTEQMSLFDAPEEHPILAELAKLDVYNMTPMQAMNVLVEFKQKL

Nucleotide

• Length: 2535 bp

>NTDB_id=577263 MP387_RS08425 WP_242746306.1 1726969..1729503(-) (hexA) [Streptococcus oralis strain 1648]
ATGGCAACAGAAAAGCTATCACCCGGCATGCAACAGTATGTGGATATTAAAAAACAATACCCAGATGCTTTTTTGCTTTT
TCGAATGGGTGATTTTTACGAGTTGTTCTATGAAGATGCAATTAATGCAGCGCAAATTTTAGAAATTTCCTTAACAAGTC
GGAATAAAAATGCAGAAAATCCGATACCCATGGCGGGTGTCCCCTATCATTCTGCCCAGCAGTATATCGACGTATTGATC
GAGCAGGGCTATAAGGTAGCCATAGCCGAGCAGATGGAAGATCCCAAACAAGCAGTTGGTGTTGTCAAGCGAGAGGTGGT
CCAGGTCATCACACCTGGGACGGTCGTCGATAGCAGTAAGCCGGATAGTCAGAATAATTTCTTGGTTGCCGTAGATCGCG
ATGGCAATCAATTTGGTCTGGCTTATATGGATCTAGTGACGGGTGACTTTTATGTGACGGGGCTATTGGATTTCACGTTG
GTTTGTGGGGAAATCCGTAACCTCAAGGCTCGTGAAGTGGTGCTGGGTTATGACTTGTCTGAGGAAGAAGAACAAATTTT
CAGCTGTCAGATGAATTTGGTGCTTTCTTATGAGAAAGAAGGTTTTGAGGATATTCATTTACTGGATCCACGATTGGCAG
CTGTGGAGCAAGCAGCAGCTAGTAAGCTCCTCCAGTATGTTCATCGGACCCAGATGCGGGAATTGAACCATCTTAAACCA
GTTATCCGCTATGAAATCAAAGATTTCTTGCAGATGGATTATGCGACCAAGGCTAGTCTGGATTTGGTTGAGAATGCCCG
TTCAGGCAAGAAGCAGGGGAGTCTTTTCTGGCTTTTGGATGAAACCAAGACGGCTATGGGCATGCGGCTCTTGCGTTCTT
GGATTCATCGTCCTTTGATTGATAAGGAGCGAATCGTCCAGCGTCAAGAGGTGGTGCAGGTATTTCTTGACCACTTCTTT
GAGCGTAGTGATTTAACGGACAGTCTCAAGGGTGTTTATGATATCGAACGCTTGGCTAGTCGGGTTTCGTTTGGCAAGAC
CAATCCCAAGGATCTCTTGCAGTTGGCGACTACCTTATCTAGTGTGCCAAGGATTCGGGCGATTTTAGAGGGAATGGAGC
AGCCTGCTTTAGCCTATCTCATCGCACAGTTGGATGCCATTCCAGAGTTAGAGAGCTTGATTAGCGCAGCGATAGCCCCT
GAAGCCCCTCACGTGATTACGGAAGGTGGCATTATCCGGACGGGATTTGATGAGACCTTGGATAAATACCGTCGTGTACT
CAGAGAAGGGACTAGCTGGATTGCTGAGATTGAGGCTAAGGAGAGAGAAAACTCTGGCATCAGCACGCTTAAGATTGACT
ACAATAAAAAGGACGGCTACTATTTCCATGTGACCAATTCGCAACTGGGAAATGTGCCAGCCCACTTTTTCCGCAAGGCA
ACGCTGAAAAACTCGGAACGCTTTGGTACCGAAGAATTGGCCCGTATCGAGGGAGATATGCTGGAGGCGCGTGAGAAGTC
AGCCAACCTAGAATATGAAATCTTTATGCGCATCCGTGAGGAAGTCAGCAAGTACATCCAGCGTTTGCAGGCTTTAGCCC
AAGGAATTGCGACGGTTGATGTTTTGCAAAGTCTGGCAGTTGTGGCTGAAACCCAGCATTTGATTCGACCTGAGTTTGGA
GAGGATTCACAAATCGCTATCCAGAAAGGTCGCCATGCTGTCGTCGAAAAGGTTATGGGAGCGCAGACCTACATTCCAAA
CAGTATCCAGATGTCAGAAGATACCAGCATTCAACTGATTACGGGACCCAACATGAGCGGGAAGTCAACCTACATGCGCC
AGCTAGCCATGACGGCGGTTATGGCCCAGCTGGGTTCTTATGTGCCGGCAGAAAGCGCCCATTTGCCGATCTTCGATGCC
ATCTTTACCCGTATCGGAGCAGCAGATGACTTGGTTTCAGGTCAATCAACCTTCATGGTGGAGATGATGGAGGCCAACAA
TGCCATTTCGCATGCGACCAAGGACTCCTTGATTCTCTTCGATGAATTGGGACGGGGAACGGCAACTTATGACGGGATGG
CTCTCGCCCAGTCCATCATCGAATACATCCATAAACATATCGGAGCTAAAACCCTCTTTGCGACCCACTATCATGAGTTG
ACTAGTCTGGAGTCCAGTTTGGAACACTTGGTCAATGTCCACGTGGCAACCTTGGAGCAGGATGGACAGGTTACCTTCCT
TCACAAGATTGAACCAGGGCCAGCTGACAAATCCTATGGTATCCACGTTGCTAAGATTGCTGGTTTACCAGCAGAACTTT
TAGCAAGGGCGGATAAGATTTTGACCCAACTGGAGAATCAAGGGACGGAAAGTCCTGTTCCCATTAGAGAAACAAGTGCT
GTCACAGAGCAGATGTCACTCTTTGATGCGCCTGAAGAACATCCTATCCTAGCAGAATTAGCTAAACTGGATGTGTACAA
TATGACACCTATGCAGGCTATGAATGTCTTAGTTGAGTTCAAACAAAAATTATAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain II (MutS_II) (126-239)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	95.735	100	0.957
mutS	Pseudomonas stutzeri strain ATCC 17587	37.123	100	0.379