Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MP387_RS07525 Genome accession   NZ_CP094226
Coordinates   1533836..1534468 (-) Length   210 a.a.
NCBI ID   WP_042902850.1    Uniprot ID   -
Organism   Streptococcus oralis strain 1648     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1528836..1539468
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP387_RS07510 (MP387_07510) recD/recD2/recDB 1529388..1531757 (+) 2370 WP_242745968.1 ATP-dependent RecD-like DNA helicase Machinery gene
  MP387_RS07515 (MP387_07515) tig 1531805..1533088 (-) 1284 WP_000116506.1 trigger factor -
  MP387_RS07520 (MP387_07520) - 1533179..1533835 (-) 657 WP_242745970.1 DNA alkylation repair protein -
  MP387_RS07525 (MP387_07525) vraR 1533836..1534468 (-) 633 WP_042902850.1 response regulator transcription factor Regulator
  MP387_RS07530 (MP387_07530) - 1534478..1535476 (-) 999 WP_242745975.1 sensor histidine kinase -
  MP387_RS07535 (MP387_07535) liaF 1535473..1536171 (-) 699 WP_242745991.1 cell wall-active antibiotics response protein LiaF -
  MP387_RS07540 (MP387_07540) fni 1536338..1537339 (-) 1002 WP_242745994.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  MP387_RS07545 (MP387_07545) - 1537323..1538330 (-) 1008 WP_242745997.1 phosphomevalonate kinase -
  MP387_RS07550 (MP387_07550) mvaD 1538317..1539270 (-) 954 WP_242745999.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23602.24 Da        Isoelectric Point: 4.8993

>NTDB_id=577247 MP387_RS07525 WP_042902850.1 1533836..1534468(-) (vraR) [Streptococcus oralis strain 1648]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEAANGAQGIELALKLRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLNAGAKGYMLKTSSADELLHAVRKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=577247 MP387_RS07525 WP_042902850.1 1533836..1534468(-) (vraR) [Streptococcus oralis strain 1648]
ATGAAAATTTTACTTGTAGATGACCATGAAATGGTTCGATTGGGCTTGAAAAGCTATTTTGATCTCCAAGACGATGTGGA
AGTTGTGGGCGAGGCTGCCAATGGGGCTCAAGGTATTGAGTTGGCCTTGAAACTGCGTCCAGATGTCATTGTCATGGATA
TCGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCCATCCTCAAAGAATGGCCTGAAGCCAAGATTTTGATTGTA
ACTTCTTACTTGGACAATGAAAAAATCATGCCAGTCTTGAATGCGGGTGCCAAAGGTTATATGCTCAAGACTTCTAGTGC
AGACGAACTGCTCCATGCCGTTCGTAAGGTGGCTGCTGGAGAGCTGGCTATTGAACAAGAGGTCAGCAAGAAGGTTGAAT
ACCACCGTAATCATATGGAGCTTCATGAGGAGCTGACTGCGCGTGAGCGAGACGTGCTCCAACTCATCGCTAAGGGCTAC
GAAAATCAACGCATTGCAGATGAACTCTTCATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATCCTAGCCAAGCT
TGAGGTCAGTGATCGCACCCAGGCTGCGGTCTATGCCTTTCAGCACCACTTGGTCGGGCAGGAGGACTTTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-115)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41