Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MP387_RS04170 Genome accession   NZ_CP094226
Coordinates   854100..856088 (+) Length   662 a.a.
NCBI ID   WP_242747896.1    Uniprot ID   -
Organism   Streptococcus oralis strain 1648     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 849100..861088
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP387_RS04155 (MP387_04155) zwf 849377..850864 (-) 1488 WP_242747891.1 glucose-6-phosphate dehydrogenase -
  MP387_RS04160 (MP387_04160) - 851014..851754 (-) 741 WP_001096337.1 amino acid ABC transporter ATP-binding protein -
  MP387_RS04165 (MP387_04165) - 851754..853919 (-) 2166 WP_242747893.1 ABC transporter substrate-binding protein/permease -
  MP387_RS04170 (MP387_04170) uvrB 854100..856088 (+) 1989 WP_242747896.1 excinuclease ABC subunit UvrB Machinery gene
  MP387_RS04175 (MP387_04175) - 856129..857166 (+) 1038 WP_242747898.1 acyltransferase -
  MP387_RS09145 (MP387_04180) - 857295..857408 (+) 114 Protein_774 UvrB/UvrC motif-containing protein -
  MP387_RS04185 (MP387_04185) - 857423..858049 (+) 627 WP_242747900.1 NAD(P)H-dependent oxidoreductase -
  MP387_RS04190 (MP387_04190) - 858242..858961 (+) 720 WP_242747902.1 hypothetical protein -
  MP387_RS04195 (MP387_04195) - 859034..859537 (+) 504 WP_242747904.1 hypothetical protein -
  MP387_RS04200 (MP387_04200) - 860033..860590 (+) 558 WP_242747905.1 hypothetical protein -
  MP387_RS04205 (MP387_04205) - 860568..861008 (+) 441 WP_242747907.1 hypothetical protein -

Sequence

Protein


Download         Length: 662 a.a.        Molecular weight: 75832.97 Da        Isoelectric Point: 4.6080

>NTDB_id=577215 MP387_RS04170 WP_242747896.1 854100..856088(+) (uvrB) [Streptococcus oralis strain 1648]
MINRITDNKFKLVSKYEPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYS
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFVTNDDHMEIAIAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
MTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQERKELVKKLEKQMQEAV
EVLDFELAAQIRDMMLEVKALN

Nucleotide


Download         Length: 1989 bp        

>NTDB_id=577215 MP387_RS04170 WP_242747896.1 854100..856088(+) (uvrB) [Streptococcus oralis strain 1648]
ATGATAAATCGAATTACAGATAATAAATTTAAACTAGTATCAAAATATGAACCTTCAGGAGATCAACCCCAAGCGATTGA
GCAGTTGGTTGACAATATCGAGGGTGGAGAAAAGGCACAGATTTTGATGGGGGCGACGGGTACAGGGAAGACCTACACCA
TGAGTCAGGTCATTTCCAAAGTAAATAAACCTACTTTGGTCATTGCCCATAACAAAACCCTAGCTGGTCAGCTCTATGGA
GAGTTTAAGGAATTTTTCCCTGAAAATGCTGTTGAGTACTTTGTGTCTTACTATGATTATTATCAACCAGAGGCCTATGT
CCCTTCGAGCGATACCTATATTGAGAAGGATAGCTCGGTCAATGATGAGATTGACAAGCTTCGACACTCAGCGACTTCAG
CTCTTCTGGAGCGTAACGATGTCATCGTCGTAGCTTCTGTCTCTTGTATCTATGGTTTGGGTTCGCCCAAGGAATATTCT
GATAGTGTTGTTAGTCTTCGTCCAGGTCTTGAGATTTCTCGTGACAAACTTTTAAATGATTTAGTTGACATTCAGTTTGA
ACGCAATGATATTGATTTCCAACGGGGAAGATTTCGCGTTCGTGGGGATGTGGTGGAGATTTTCCCAGCTTCCCGTGATG
AACACGCTTTTCGAGTAGAGTTTTTCGGGGATGAAATTGATCGTATCCGTGAAGTTGAGGCTTTGACAGGTCAGGTATTG
GGAGAAGTGGATCATTTGGCGATTTTCCCTGCCACTCACTTTGTGACCAATGATGACCACATGGAGATTGCCATTGCTAA
GATTCAGGCAGAGTTGGAGGAGCAGTTGGCTGTCTTTGAAAAGGAAGGCAAACTGCTAGAAGCTCAGCGTTTGAAACAGC
GGACAGAGTATGATATTGAGATGCTACGTGAGATGGGTTATACCAACGGTGTTGAAAACTATTCTCGTCACATGGATGGT
CGTAGCGAAGGAGAGCCTCCTTATACGCTTCTTGATTTCTTCCCAGATGATTTCTTAATCATGATTGATGAAAGTCACAT
GACCATGGGGCAGATTAAGGGCATGTACAATGGAGACCGTTCACGTAAGGAAATGTTGGTCAATTATGGTTTCCGTTTGC
CTTCTGCCTTGGACAATCGTCCTCTCCGTCGGGAAGAGTTTGAAAGTCATGTTCACCAGATTGTATATGTTTCAGCGACA
CCAGGTGACTATGAAAATGAACAGACCGAGACAGTGATTGAGCAAATCATTCGTCCAACAGGGCTTCTAGACCCAGAAGT
GGAAGTTCGTCCGACTATGGGACAGATTGATGACCTCCTAGGTGAAATCAATGCCCGTGTTGAAAAGAATGAACGGACCT
TTATCACCACTTTGACTAAGAAAATGGCTGAAGACTTAACCGACTACTTCAAAGAAATGGGCATCAAGGTCAAGTACATG
CACTCGGATATCAAGACTTTGGAGCGGACGGAGATTATCCGTGACCTACGCTTGGGTGTTTTTGATGTCTTGGTCGGAAT
CAACCTGCTCCGTGAAGGGATTGACGTTCCTGAAGTAAGTTTAGTAGCCATTCTCGATGCCGACAAGGAAGGATTCCTAC
GTAACGAACGTGGCTTAATCCAGACCATTGGACGTGCCGCCCGTAACAGTGAAGGTCATGTCATCATGTATGCTGATACC
ATGACCCAGTCTATGCAACGTGCTATCGATGAAACTGCCCGCCGTCGGAAAATCCAGATGGCCTATAATGAAGAACACGG
TATTGTGCCTCAGACAATCAAGAAAGAAATCCGTGACCTGATTGCTGTGACCAAGGCAGTTGCTAAGGAAGAGGACAAGG
AAGTCGATATCAATAGCCTCAACAAACAAGAGCGCAAGGAACTCGTTAAAAAACTGGAAAAACAAATGCAAGAAGCCGTC
GAAGTGCTTGACTTTGAACTCGCAGCTCAGATTCGTGATATGATGTTGGAAGTGAAGGCGTTAAACTGA

Domains

Predicted by InterProScan.

Type III restriction enzyme, res subunit (ResIII)

(17-143)

UvrB/uvrC motif (UVR)

(626-660)

Helicase conserved C-terminal domain (Helicase_C)

(443-549)

Ultra-violet resistance protein B (UvrB)

(556-598)

UvrB interaction domain (UvrB_inter)

(164-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

98.943

100

0.989
  uvrB Streptococcus pneumoniae D39

98.943

100

0.989
  uvrB Streptococcus pneumoniae TIGR4

98.792

100

0.988