Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MPF93_RS01945 Genome accession   NZ_CP094178
Coordinates   385831..387807 (+) Length   658 a.a.
NCBI ID   WP_245074696.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe060     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 380831..392807
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPF93_RS01930 (MPF93_01930) ggt 381924..383627 (+) 1704 WP_154497546.1 gamma-glutamyltransferase -
  MPF93_RS01935 (MPF93_01935) - 383912..384682 (+) 771 WP_000540152.1 HP1117 family Sel1-like repeat protein -
  MPF93_RS01940 (MPF93_01940) - 385195..385790 (+) 596 Protein_376 DUF1542 domain-containing protein -
  MPF93_RS01945 (MPF93_01945) uvrB 385831..387807 (+) 1977 WP_245074696.1 excinuclease ABC subunit UvrB Machinery gene
  MPF93_RS01950 (MPF93_01950) - 387818..388651 (-) 834 WP_245074193.1 outer membrane protein -
  MPF93_RS01955 (MPF93_01955) purB 388714..390036 (-) 1323 WP_000893894.1 adenylosuccinate lyase -
  MPF93_RS01960 (MPF93_01960) - 390146..391090 (-) 945 WP_050835757.1 thiamine pyrophosphate-dependent enzyme -
  MPF93_RS01965 (MPF93_01965) - 391103..392326 (-) 1224 WP_017280722.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  MPF93_RS01970 (MPF93_01970) - 392336..392728 (-) 393 WP_128018404.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75953.44 Da        Isoelectric Point: 6.9279

>NTDB_id=577140 MPF93_RS01945 WP_245074696.1 385831..387807(+) (uvrB) [Helicobacter pylori strain Hpfe060]
MPLFDLKSPYPPAGDQPKAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIANTNKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSAATSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALEKNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKNNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKLHHITPKTVTRALEEELKLRDDEIKIAKALKKDKIPKSEREKIIKELDKKMREYAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=577140 MPF93_RS01945 WP_245074696.1 385831..387807(+) (uvrB) [Helicobacter pylori strain Hpfe060]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCAAAAGCCATAGAAGCCTTAACGAAGAGCTT
AAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGGAGCGGTAAAACTTATACGATGGCCAATATCATCGCTA
ATACCAACAAACCCACTCTGATCATGAGCCATAATAAGACCTTATGCGCACAGCTCTATAGCGAGTTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGATTGAGTGCGGCCACCTCACTTTTAGGTTATGATG
ATGTGATTGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCGCTTATAAGAGCTTTTTATTAAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGAGGGAGCTTCAGGGCGACCGGAGAATGCGTGGATATTTTCCCAGCTTATAATGACGCTGAATTTATCAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCTTTAGAAAAAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAGTGAGAGGTTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TTTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCGCAACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTTACAGGCAAAGCCCCTAATGAAACG
CCTTTTTGTTTGTTTGATTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGAGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGTGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCTACGCCCAATAAG
TTAGAATTAGAGCTTTCTAAGAATAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTCATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAAGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGGAATCACATCATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
CTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGACGAGCCGCTAGAAACGCCAATGGCAAGGTTTTGTTATACGCTAAAAAAATCACC
CAAAGCATGCAAAAAGCCTTTGAAATTACGAGCTACAGGCGCGCTAAGCAAGAAGAATTTAATAAGCTTCATCATATCAC
CCCCAAAACCGTTACTCGCGCTTTAGAAGAGGAGTTGAAATTAAGAGACGATGAGATTAAAATCGCTAAAGCCTTAAAAA
AGGACAAAATACCTAAAAGCGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATACGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGATGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

UvrB interaction domain (UvrB_inter)

(159-248)

Ultra-violet resistance protein B (UvrB)

(554-595)

Type III restriction enzyme, res subunit (ResIII)

(15-123)

UvrB/uvrC motif (UVR)

(623-657)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.321

100

0.497
  uvrB Streptococcus pneumoniae D39

49.321

100

0.497
  uvrB Streptococcus pneumoniae TIGR4

49.321

100

0.497