Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MPG23_RS01880 Genome accession   NZ_CP094172
Coordinates   379029..381005 (+) Length   658 a.a.
NCBI ID   WP_245089026.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe0002     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 374029..386005
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG23_RS01865 (MPG23_01865) ggt 375124..376827 (+) 1704 WP_015642494.1 gamma-glutamyltransferase -
  MPG23_RS01870 (MPG23_01870) - 377110..377880 (+) 771 WP_245089023.1 HP1117 family Sel1-like repeat protein -
  MPG23_RS01875 (MPG23_01875) - 378393..378979 (+) 587 Protein_366 DUF1542 domain-containing protein -
  MPG23_RS01880 (MPG23_01880) uvrB 379029..381005 (+) 1977 WP_245089026.1 excinuclease ABC subunit UvrB Machinery gene
  MPG23_RS01885 (MPG23_01885) - 381002..381835 (-) 834 WP_245089029.1 outer membrane protein -
  MPG23_RS01890 (MPG23_01890) purB 381899..383221 (-) 1323 WP_245064803.1 adenylosuccinate lyase -
  MPG23_RS01895 (MPG23_01895) - 383331..384275 (-) 945 WP_120927956.1 thiamine pyrophosphate-dependent enzyme -
  MPG23_RS01900 (MPG23_01900) - 384288..385511 (-) 1224 WP_245089032.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  MPG23_RS01905 (MPG23_01905) - 385522..385914 (-) 393 WP_154450205.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75919.53 Da        Isoelectric Point: 7.0841

>NTDB_id=576972 MPG23_RS01880 WP_245089026.1 379029..381005(+) (uvrB) [Helicobacter pylori strain Hpfe0002]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIAKINKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSAATSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALEKNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKLHHITPKTVTRALEEELKLRDDEVKIAKALKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=576972 MPG23_RS01880 WP_245089026.1 379029..381005(+) (uvrB) [Helicobacter pylori strain Hpfe0002]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCCTTAACGAAAAGCTT
AAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGGAGCGGTAAAACTTATACGATGGCCAATATCATCGCTA
AGATCAACAAACCCACTCTGATCATGAGCCATAATAAGACCTTATGCGCGCAGCTTTATAGCGAATTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGATTGAGCGCGGCCACCTCACTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCGCTTATAAGAGTTTTTTATTAAAGCTAGTAGAAATGGGTTATAGCCGTAATGAGGTGGTGTT
TGATAGGGGGAGCTTTAGAGCGACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATCAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCTTTAGAAAAAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAGTGAGAGGTTGAATTTGGCCATTAAAAGCATTGAAGATGAACTCGC
TTTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGTGCAACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTTACAGGCAAAGCCCCTAATGAAACG
CCTTTTTGTTTGTTTGATTATTTGGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGAGGGATGTATGCGGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCCAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCTACGCCCAATAAG
CTAGAATTAGAGCTTTCCAAAAAGAATGTCGCTGAGCAAATTATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAAGATTTATTTGATGAAATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTTATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAAGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGAAATCACATCATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
TTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCTAATGGCAAGGTTTTATTATACGCTAAAAAAATCACC
CAAAGCATGCAAAAAGCCTTTGAAATTACGAGCTACAGGCGCGCTAAGCAAGAAGAATTTAATAAGCTTCATCATATCAC
TCCCAAAACCGTTACTCGCGCTTTAGAAGAGGAGTTGAAATTAAGAGACGATGAGGTTAAAATCGCTAAAGCCTTAAAAA
AGGACAAAATCCCTAAAAGTGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGATGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

Type III restriction enzyme, res subunit (ResIII)

(15-123)

UvrB/uvrC motif (UVR)

(623-657)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

UvrB interaction domain (UvrB_inter)

(159-248)

Ultra-violet resistance protein B (UvrB)

(554-595)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.472

100

0.498
  uvrB Streptococcus pneumoniae D39

49.472

100

0.498
  uvrB Streptococcus pneumoniae TIGR4

49.472

100

0.498