Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MPG03_RS00600 Genome accession   NZ_CP094160
Coordinates   126007..127983 (+) Length   658 a.a.
NCBI ID   WP_245021291.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe0016     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 121007..132983
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG03_RS00585 (MPG03_00585) ggt 122097..123800 (+) 1704 WP_245021289.1 gamma-glutamyltransferase -
  MPG03_RS00590 (MPG03_00590) - 124087..124857 (+) 771 WP_245021290.1 tetratricopeptide repeat protein -
  MPG03_RS00595 (MPG03_00595) - 125367..125966 (+) 600 Protein_117 DUF1542 domain-containing protein -
  MPG03_RS00600 (MPG03_00600) uvrB 126007..127983 (+) 1977 WP_245021291.1 excinuclease ABC subunit UvrB Machinery gene
  MPG03_RS00605 (MPG03_00605) - 127994..128827 (-) 834 WP_245021292.1 outer membrane protein -
  MPG03_RS00610 (MPG03_00610) purB 128889..130211 (-) 1323 WP_245021293.1 adenylosuccinate lyase -
  MPG03_RS00615 (MPG03_00615) - 130321..131265 (-) 945 WP_000238160.1 thiamine pyrophosphate-dependent enzyme -
  MPG03_RS00620 (MPG03_00620) - 131278..132501 (-) 1224 WP_245021294.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  MPG03_RS00625 (MPG03_00625) - 132511..132903 (-) 393 WP_126474611.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75882.40 Da        Isoelectric Point: 6.7783

>NTDB_id=576649 MPG03_RS00600 WP_245021291.1 126007..127983(+) (uvrB) [Helicobacter pylori strain Hpfe0016]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIANTNKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSAATSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKCLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKLHHITPKTVTRALEEELKLRDDEIKIAKALKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=576649 MPG03_RS00600 WP_245021291.1 126007..127983(+) (uvrB) [Helicobacter pylori strain Hpfe0016]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCCCAAGCTATAGAAGCCTTAACGAAGAGCTT
AAAAAATAACAACCATTATCAGACTTTAGTGGGGGTTACAGGGAGCGGTAAGACTTATACGATGGCTAATATCATCGCTA
ATACCAACAAGCCCACTCTGATCATGAGCCATAATAAGACCTTATGCGCGCAGCTCTATAGCGAGTTTAAAGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGATTGAGCGCGGCTACCTCACTTTTAGGTTATGATG
ATGTGATTGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCGCTTATAAGAGCTTTTTATTAAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGTTTTAGAGCGACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATCAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCTTTAGAAAGAAATGAAATCAAGTGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAGTGAGAGGTTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TTTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGTGCAACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTTACAGGCAAAGCCCCTAATGAAACA
CCTTTTTGTTTGTTTGATTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGAGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCTACGCCCAATAAG
CTAGAATTAGAGCTTTCCAAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTTATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAAGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGAAATCACATCATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
TTTAAGAGAAGGGCTGGATTTGCCTGAAGTTTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCTAATGGCAAGGTTTTATTATACGCTAAAAAAATCACC
CAAAGCATGCAAAAAGCCTTTGAAATTACAAGCTACAGGCGCGCTAAGCAAGAAGAGTTTAATAAGCTTCATCATATCAC
CCCCAAAACCGTTACTCGCGCTTTAGAAGAGGAGTTGAAATTAAGAGACGATGAGATTAAAATCGCTAAAGCCTTAAAAA
AGGACAAAATCCCTAAAAGCGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGATGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(159-248)

UvrB/uvrC motif (UVR)

(623-657)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

Ultra-violet resistance protein B (UvrB)

(554-595)

Type III restriction enzyme, res subunit (ResIII)

(15-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.472

100

0.498
  uvrB Streptococcus pneumoniae D39

49.472

100

0.498
  uvrB Streptococcus pneumoniae TIGR4

49.472

100

0.498