Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   LEUCM_RS00665 Genome accession   NZ_AP017929
Coordinates   110284..112242 (-) Length   652 a.a.
NCBI ID   WP_025016298.1    Uniprot ID   -
Organism   Latilactobacillus sakei subsp. sakei DSM 20017 = JCM 1157 strain LT-13     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 105284..117242
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LEUCM_RS00635 (LACBS_00105) - 105687..106208 (-) 522 WP_016264644.1 GNAT family N-acetyltransferase -
  LEUCM_RS00640 (LACBS_00106) queA 106235..107266 (-) 1032 WP_011374077.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  LEUCM_RS00645 (LACBS_00107) ruvB 107281..108288 (-) 1008 WP_016264643.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  LEUCM_RS00650 (LACBS_00108) ruvA 108301..108912 (-) 612 WP_056936468.1 Holliday junction branch migration protein RuvA Machinery gene
  LEUCM_RS00655 (LACBS_00109) - 109163..109726 (-) 564 WP_016264641.1 TIGR00730 family Rossman fold protein -
  LEUCM_RS00660 (LACBS_00110) - 109739..110284 (-) 546 WP_016264640.1 nucleoside triphosphate pyrophosphatase -
  LEUCM_RS00665 (LACBS_00111) hexB 110284..112242 (-) 1959 WP_025016298.1 DNA mismatch repair endonuclease MutL Machinery gene
  LEUCM_RS00670 (LACBS_00112) mutS 112266..114869 (-) 2604 Protein_101 DNA mismatch repair protein MutS -
  LEUCM_RS00675 (LACBS_00114) - 114891..115367 (-) 477 Protein_102 YmdB family metallophosphoesterase -
  LEUCM_RS00680 (LACBS_00115) - 115461..116390 (+) 930 WP_085391442.1 IS30-like element ISLpl1 family transposase -
  LEUCM_RS00685 (LACBS_00116) - 116406..116744 (-) 339 Protein_104 YmdB family metallophosphoesterase -

Sequence

Protein


Download         Length: 652 a.a.        Molecular weight: 72749.18 Da        Isoelectric Point: 5.4280

>NTDB_id=57641 LEUCM_RS00665 WP_025016298.1 110284..112242(-) (hexB) [Latilactobacillus sakei subsp. sakei DSM 20017 = JCM 1157 strain LT-13]
MGKIHELSEILSNQIAAGEVIERPASVVKELVENAIDANSTQVDIVVEQAGLQMIQVIDNGDGIEPEDVPVAFKRHATSK
IATRQDLFKIQSLGFRGEALASIASVSDLTIETATADSLGTFAHFKGGLLEEQKTNPIRPGTAITVRDLFFNTPARLKYV
KTFQTELANIVDIVNRLAMSHPQIAFTLTNDDHLLLKTAGNNDLKQTIAGIYGVTMAKKLLAVSASDLDFKLTGYVSLPE
LTRATRNYLSILINGRFIKNYQLNKAIIKGYGSKLMVGRYPIAVLAIEMDPLLIDVNVHPTKQEVRLSKETALMTLIEGA
IKERLATENLIPDAMQNLKRTKTVDVDQLQMNLNQITQERRHPSGTVRPVSPMPIPVKTVTPEIAETETPLAAPTAKAPS
MTPERPLFEQPQALAEWDQKYATEAVGKPFGDQVIDETDESEENVVEPTVRFPELRYIGQLHSTFLLAEGEDGFYILDQH
AAQERIKYEYYREKIGEVSTSVQNLLVPLVLEYPNSDALKIQEKTELLASVGIQLENFGQNSFVVHSHPTWIEQGQEEMT
IRGMIDDVLKDGRISIAQFREKTAIMMSCKQSIKAHHHLDDTQAKALLADLAKTENPFNCPHGRPVLIHYTQKDLEKMFK
RIQEPHHSWEGE

Nucleotide


Download         Length: 1959 bp        

>NTDB_id=57641 LEUCM_RS00665 WP_025016298.1 110284..112242(-) (hexB) [Latilactobacillus sakei subsp. sakei DSM 20017 = JCM 1157 strain LT-13]
ATGGGGAAAATTCATGAACTGTCGGAAATTCTGAGTAATCAAATTGCGGCGGGGGAAGTGATTGAACGCCCCGCCTCAGT
GGTCAAGGAATTGGTTGAAAACGCGATTGATGCTAATAGTACGCAAGTCGATATTGTTGTTGAACAGGCCGGTTTACAGA
TGATTCAAGTGATCGATAACGGTGACGGGATTGAACCAGAAGATGTGCCAGTCGCCTTTAAGCGGCATGCCACCAGTAAG
ATTGCGACTCGGCAAGATTTGTTCAAGATTCAATCGCTAGGGTTTCGGGGTGAAGCGTTAGCTAGTATCGCGTCCGTTTC
CGATTTAACGATTGAAACGGCAACTGCGGACTCTCTAGGAACCTTTGCTCATTTTAAGGGTGGTCTGTTAGAGGAACAAA
AAACAAATCCGATTCGACCGGGGACGGCGATTACGGTGCGGGATTTATTCTTTAATACACCGGCACGATTGAAATACGTG
AAGACTTTTCAAACCGAATTGGCGAATATCGTCGATATCGTCAATCGGCTAGCAATGAGTCATCCACAGATTGCCTTTAC
GCTAACCAATGATGACCATCTACTTTTAAAAACGGCCGGCAACAATGATTTAAAACAAACGATTGCTGGTATTTATGGCG
TCACCATGGCCAAGAAACTCTTAGCCGTGAGTGCTTCGGATTTAGATTTTAAACTAACGGGCTACGTGTCATTGCCGGAA
TTAACGCGGGCAACGCGCAATTATTTGTCGATTTTAATTAATGGTCGGTTTATTAAAAATTACCAATTGAATAAGGCCAT
TATCAAGGGCTACGGTTCTAAATTGATGGTCGGACGCTATCCAATCGCCGTCTTAGCGATTGAGATGGATCCGCTATTGA
TCGATGTCAACGTGCATCCAACAAAACAGGAAGTCCGCTTAAGCAAAGAAACTGCCTTGATGACCTTGATTGAAGGGGCA
ATCAAAGAAAGACTGGCAACCGAGAATTTAATTCCAGATGCCATGCAGAATTTGAAACGGACCAAGACGGTAGATGTTGA
TCAGCTCCAGATGAATTTAAACCAAATTACACAAGAACGACGGCACCCAAGCGGTACGGTGCGACCAGTCAGTCCAATGC
CAATCCCAGTAAAAACGGTAACACCCGAAATTGCGGAAACCGAAACGCCGTTAGCCGCACCAACTGCTAAAGCGCCATCG
ATGACACCGGAGCGGCCCTTATTTGAGCAACCCCAGGCATTGGCCGAGTGGGATCAGAAGTACGCGACAGAAGCGGTTGG
AAAGCCGTTTGGTGATCAAGTGATAGACGAAACGGACGAAAGTGAAGAAAACGTAGTCGAACCCACTGTTCGGTTCCCAG
AGTTACGCTACATTGGGCAACTGCATAGTACTTTCTTATTAGCGGAAGGCGAAGATGGCTTTTATATCTTGGATCAACAC
GCTGCGCAAGAACGGATTAAGTACGAATATTACCGAGAAAAAATTGGGGAAGTCAGCACCTCTGTGCAAAACTTGTTAGT
ACCACTTGTTTTGGAATATCCGAATAGTGATGCGCTAAAGATTCAGGAAAAAACTGAACTTTTAGCCTCAGTCGGAATCC
AATTAGAAAATTTCGGGCAGAATAGTTTTGTGGTCCACAGTCACCCAACTTGGATTGAACAGGGACAAGAGGAAATGACG
ATTCGTGGGATGATTGACGATGTTTTAAAAGACGGTCGCATTAGCATTGCCCAATTCCGTGAGAAGACGGCGATTATGAT
GAGCTGTAAGCAATCGATTAAAGCGCACCATCATTTAGATGATACCCAGGCTAAAGCACTTTTAGCTGATCTAGCGAAGA
CCGAGAATCCGTTTAATTGTCCCCATGGGCGCCCGGTTTTGATTCACTATACGCAAAAAGATTTGGAAAAGATGTTTAAA
CGGATTCAAGAACCACATCATAGTTGGGAGGGCGAATAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(455-599)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(208-325)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-136)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

50.381

100

0.508

Multiple sequence alignment