Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MPG27_RS01980 Genome accession   NZ_CP094147
Coordinates   395887..397863 (+) Length   658 a.a.
NCBI ID   WP_245042947.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe027     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 390887..402863
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG27_RS01965 (MPG27_01965) ggt 391986..393689 (+) 1704 WP_120836501.1 gamma-glutamyltransferase -
  MPG27_RS01970 (MPG27_01970) - 393967..394737 (+) 771 WP_245042945.1 tetratricopeptide repeat protein -
  MPG27_RS07640 - 395640..395762 (+) 123 WP_342369795.1 histidinol dehydrogenase -
  MPG27_RS01980 (MPG27_01980) uvrB 395887..397863 (+) 1977 WP_245042947.1 excinuclease ABC subunit UvrB Machinery gene
  MPG27_RS01985 (MPG27_01985) - 397860..398693 (-) 834 WP_245042949.1 outer membrane protein -
  MPG27_RS01990 (MPG27_01990) purB 398764..400086 (-) 1323 WP_245042951.1 adenylosuccinate lyase -
  MPG27_RS01995 (MPG27_01995) - 400195..401139 (-) 945 WP_000238169.1 thiamine pyrophosphate-dependent enzyme -
  MPG27_RS02000 (MPG27_02000) - 401152..402375 (-) 1224 WP_245042961.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  MPG27_RS02005 (MPG27_02005) - 402385..402777 (-) 393 WP_000656168.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75977.48 Da        Isoelectric Point: 6.7808

>NTDB_id=576276 MPG27_RS01980 WP_245042947.1 395887..397863(+) (uvrB) [Helicobacter pylori strain Hpfe027]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIANINKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSAATSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYATSQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSQKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKLHHITPKTVTRALEEELKLRDDEIKIAKALKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=576276 MPG27_RS01980 WP_245042947.1 395887..397863(+) (uvrB) [Helicobacter pylori strain Hpfe027]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCCCAAGCTATAGAAGCCTTAACGAAGAGCTT
AAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGGAGCGGTAAGACTTATACGATGGCTAATATCATCGCTA
ACATCAACAAACCCACTCTGATCATGAGCCATAATAAGACCTTATGCGCGCAGCTCTATAGCGAGTTTAAGGCGTTTTTT
CCGCATAATAGAGTGGAGTATTTTATCTCCCACTTTGACTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGGTTGAGCGCAGCCACCTCACTTTTAGGTTATGATG
ATGTGATTGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCGCTTATAAGAGTTTTTTATTAAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGCTTCAGGGCGACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATCAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCTTTAGAAAGAAATGAAATCAAACGCTTGGATTCTGTC
ATGCTTTATGCGACCAGTCAGTTTGCCGTAGGGAGTGAGAGACTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TTTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCGCAACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTTACAGGTAAAGCCCCTAATGAAACG
CCTTTTTGTTTGTTTGATTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGAGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCCACGCCCAATAAG
CTAGAATTAGAGCTTTCTCAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTTATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCCGAATGGGGCTTGAAGGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGGAATCACATCATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
CTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCCAATGGCAAGGTTTTATTATACGCTAAAAAAATCACC
CAAAGCATGCAAAAAGCCTTTGAAATTACGAGCTACAGGCGTGCTAAGCAAGAAGAGTTTAATAAGCTTCATCATATCAC
CCCCAAAACCGTTACTCGCGCTTTAGAAGAGGAGTTGAAATTAAGAGACGATGAGATTAAAATCGCTAAAGCCTTAAAAA
AGGACAAAATACCTAAAAGCGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTA
GATTTTGAAGAAGCGATGCGTTTGAGAGATGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(623-657)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

Type III restriction enzyme, res subunit (ResIII)

(15-123)

UvrB interaction domain (UvrB_inter)

(159-248)

Ultra-violet resistance protein B (UvrB)

(554-595)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.321

100

0.497
  uvrB Streptococcus pneumoniae TIGR4

49.321

100

0.497
  uvrB Streptococcus pneumoniae D39

49.321

100

0.497