Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MPG35_RS01875 Genome accession   NZ_CP094138
Coordinates   377056..379032 (+) Length   658 a.a.
NCBI ID   WP_231208835.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe037     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 372056..384032
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG35_RS01860 (MPG35_01860) ggt 373074..374777 (+) 1704 WP_245019784.1 gamma-glutamyltransferase -
  MPG35_RS01865 (MPG35_01865) - 375062..375832 (+) 771 WP_154413557.1 HP1117 family Sel1-like repeat protein -
  MPG35_RS01870 (MPG35_01870) - 376807..376938 (+) 132 WP_180636992.1 histidinol dehydrogenase -
  MPG35_RS01875 (MPG35_01875) uvrB 377056..379032 (+) 1977 WP_231208835.1 excinuclease ABC subunit UvrB Machinery gene
  MPG35_RS01880 (MPG35_01880) - 379029..379862 (-) 834 WP_245019785.1 outer membrane protein -
  MPG35_RS01885 (MPG35_01885) purB 379933..381255 (-) 1323 WP_245019786.1 adenylosuccinate lyase -
  MPG35_RS01890 (MPG35_01890) - 381365..382309 (-) 945 WP_245019787.1 thiamine pyrophosphate-dependent enzyme -
  MPG35_RS01895 (MPG35_01895) - 382322..383545 (-) 1224 WP_050841301.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  MPG35_RS01900 (MPG35_01900) - 383555..383947 (-) 393 WP_000656175.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75961.57 Da        Isoelectric Point: 7.0841

>NTDB_id=576003 MPG35_RS01875 WP_231208835.1 377056..379032(+) (uvrB) [Helicobacter pylori strain Hpfe037]
MPLFDLKSPYPPAGDQPKAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIAQINKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSAATSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKLHHITPKTVTRALEEELKLRDDEIKIAKALKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=576003 MPG35_RS01875 WP_231208835.1 377056..379032(+) (uvrB) [Helicobacter pylori strain Hpfe037]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCAAAAGCCATAGAAGCCTTAACGAAGAGCTT
AAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGGAGCGGTAAGACTTATACGATGGCTAATATCATCGCTC
AAATCAATAAACCCACTCTGATCATGAGCCATAATAAGACCTTATGCGCGCAGCTTTATAGCGAGTTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAATATTTTATCTCCCACTTTGACTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGGTTGAGTGCGGCCACCTCACTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCGCTTATAAGAGCTTTTTATTAAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGTTTTAGAGCAACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATTAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCTTTAGAAAGAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAGTGAGAGGTTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TCTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCGCAACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTTACAGGCAAAGCCCCTAATGAAACG
CCTTTTTGTTTGTTTGACTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCCACGCCCAATAAG
CTAGAATTAGAGCTTTCTAAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTTCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTTATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAGGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGGAATCACATCATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
CTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCTAATGGTAAGGTTTTATTATACGCTAAAAAAATCACC
CAAAGCATGCAAAAAGCCTTTGAAATTACGAGTTACAGGCGCGCTAAGCAAGAAGAGTTTAACAAGCTTCATCATATCAC
CCCCAAAACCGTTACTCGCGCTTTAGAAGAGGAGTTGAAATTAAGAGACGATGAGATTAAAATCGCTAAAGCCTTAAAAA
AGGACAAAATCCCTAAAAGCGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGATGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(623-657)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

Ultra-violet resistance protein B (UvrB)

(554-595)

Type III restriction enzyme, res subunit (ResIII)

(15-123)

UvrB interaction domain (UvrB_inter)

(159-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.321

100

0.497
  uvrB Streptococcus pneumoniae TIGR4

49.321

100

0.497
  uvrB Streptococcus pneumoniae D39

49.321

100

0.497