Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MPG28_RS01905 Genome accession   NZ_CP094135
Coordinates   376979..378955 (+) Length   658 a.a.
NCBI ID   WP_245079222.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe040     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 371979..383955
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG28_RS01890 (MPG28_01890) ggt 372991..374694 (+) 1704 WP_245078738.1 gamma-glutamyltransferase -
  MPG28_RS01895 (MPG28_01895) - 374979..375749 (+) 771 WP_033586945.1 HP1117 family Sel1-like repeat protein -
  MPG28_RS07625 - 376344..376757 (+) 414 Protein_366 hypothetical protein -
  MPG28_RS01900 (MPG28_01900) - 376731..376862 (+) 132 WP_245078739.1 histidinol dehydrogenase -
  MPG28_RS01905 (MPG28_01905) uvrB 376979..378955 (+) 1977 WP_245079222.1 excinuclease ABC subunit UvrB Machinery gene
  MPG28_RS01910 (MPG28_01910) - 378952..379785 (-) 834 WP_245078740.1 outer membrane protein -
  MPG28_RS01915 (MPG28_01915) purB 379847..381169 (-) 1323 WP_245078741.1 adenylosuccinate lyase -
  MPG28_RS01920 (MPG28_01920) - 381279..382223 (-) 945 WP_000238169.1 thiamine pyrophosphate-dependent enzyme -
  MPG28_RS01925 (MPG28_01925) - 382236..383459 (-) 1224 WP_000124325.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  MPG28_RS01930 (MPG28_01930) - 383469..383861 (-) 393 WP_000656174.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75961.61 Da        Isoelectric Point: 7.0841

>NTDB_id=575882 MPG28_RS01905 WP_245079222.1 376979..378955(+) (uvrB) [Helicobacter pylori strain Hpfe040]
MPLFDLKSPYPPAGDQPQVIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIAKINKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSAATSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALEKNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKLHHITPKTVTRALEEELKLRDDEIKIAKALKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=575882 MPG28_RS01905 WP_245079222.1 376979..378955(+) (uvrB) [Helicobacter pylori strain Hpfe040]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCCCAAGTCATAGAAGCCTTAACGAAAAGCTT
GAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGGAGCGGTAAGACTTATACGATGGCTAATATCATCGCTA
AGATCAATAAACCCACTCTGATCATGAGCCATAATAAGACCTTATGCGCGCAGCTTTATAGCGAGTTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGGTTGAGCGCGGCCACCTCACTTTTAGGTTATGATG
ATGTGATTGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCGCTTATAAGAGCTTTTTATTAAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGTTTTAGAGCGACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATCAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCTTTAGAAAAAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAGTGAGAGGTTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TTTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCGCAACCGGTGTGTGTAAGGGCATTGAAAATTACGCACGCCATTTTACAGGCAAAGCCCCTAATGAAACG
CCTTTTTGTTTGTTTGATTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGAGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCCACGCCCAATAAG
CTAGAATTAGAGCTTTCTAAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTTATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAAGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGAAATCACATCATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
CTTAAGAGAAGGGCTAGATTTGCCTGAAGTTTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCTAATGGCAAGGTTTTATTATACGCTAAAAAAATCACC
CAAAGCATGCAAAAAGCCTTTGAAATTACGAGCTACAGGCGCGCTAAGCAAGAAGAGTTTAATAAGCTTCATCATATCAC
CCCAAAAACCGTTACTCGCGCTTTAGAAGAGGAGTTGAAATTAAGAGATGATGAGATTAAAATCGCTAAAGCCTTAAAAA
AGGACAAAATACCTAAAAGTGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGTGCAAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGACGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(623-657)

UvrB interaction domain (UvrB_inter)

(159-248)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

Type III restriction enzyme, res subunit (ResIII)

(15-123)

Ultra-violet resistance protein B (UvrB)

(554-595)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.472

100

0.498
  uvrB Streptococcus pneumoniae D39

49.472

100

0.498
  uvrB Streptococcus pneumoniae TIGR4

49.472

100

0.498