Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MPG21_RS01875 Genome accession   NZ_CP094133
Coordinates   372269..374245 (+) Length   658 a.a.
NCBI ID   WP_245026041.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe049     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 367269..379245
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG21_RS01860 (MPG21_01860) flgK 367292..369112 (+) 1821 WP_089482349.1 flagellar hook-associated protein FlgK -
  MPG21_RS01865 (MPG21_01865) ggt 369290..370993 (+) 1704 WP_245025681.1 gamma-glutamyltransferase -
  MPG21_RS01870 (MPG21_01870) - 371276..372046 (+) 771 WP_245025683.1 tetratricopeptide repeat protein -
  MPG21_RS01875 (MPG21_01875) uvrB 372269..374245 (+) 1977 WP_245026041.1 excinuclease ABC subunit UvrB Machinery gene
  MPG21_RS01880 (MPG21_01880) - 374256..375089 (-) 834 WP_245025685.1 outer membrane protein -
  MPG21_RS01885 (MPG21_01885) purB 375160..376482 (-) 1323 WP_180479824.1 adenylosuccinate lyase -
  MPG21_RS01890 (MPG21_01890) - 376586..377530 (-) 945 WP_000238169.1 thiamine pyrophosphate-dependent enzyme -
  MPG21_RS01895 (MPG21_01895) - 377543..378766 (-) 1224 WP_245025687.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  MPG21_RS01900 (MPG21_01900) - 378777..379169 (-) 393 WP_000656175.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75977.53 Da        Isoelectric Point: 6.9241

>NTDB_id=575800 MPG21_RS01875 WP_245026041.1 372269..374245(+) (uvrB) [Helicobacter pylori strain Hpfe049]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANVIAQINKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSAATSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISTTGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKLHHITPKTVTRALEEELKLRDDEIKIAKALKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=575800 MPG21_RS01875 WP_245026041.1 372269..374245(+) (uvrB) [Helicobacter pylori strain Hpfe049]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCCTTAACGAAAAGCTT
GAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGGAGCGGTAAAACTTATACGATGGCCAATGTCATCGCTC
AAATCAACAAACCCACTCTGATCATGAGCCATAATAAGACCTTATGCGCGCAGCTTTATAGCGAGTTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGATTGAGCGCGGCCACCTCACTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCGCTTATAAGAGCTTTTTATTAAAGTTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGTTTTAGAGCGACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATTAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCTTTAGAAAGAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAGTGAGAGGTTGAATTTAGCTATTAAAAGCATTGAAGATGAACTCGC
TTTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCACAACCGGTGTGTGTAAGGGCATTGAAAATTACGCACGCCATTTTACAGGCAAAGCCCCTAATGAAACG
CCTTTTTGTTTGTTTGATTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCCACGCCCAATAAG
CTAGAATTAGAGCTTTCTAAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTTATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAGGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAACGAAATCACATCATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGAATCAATCT
CTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGACGAGCCGCTAGAAACGCCAATGGCAAGGTTTTATTATACGCTAAAAAAATCACC
CAAAGCATGCAAAAAGCCTTTGAAATTACGAGCTACAGGCGTGCTAAGCAAGAAGAGTTTAATAAGCTTCATCATATCAC
CCCCAAAACCGTTACTCGCGCTTTAGAAGAGGAGTTGAAATTAAGAGACGATGAAATTAAAATCGCTAAAGCCTTAAAAA
AGGACAAAATCCCTAAAAGCGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGTGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGACGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(623-657)

Type III restriction enzyme, res subunit (ResIII)

(15-123)

Ultra-violet resistance protein B (UvrB)

(554-595)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

UvrB interaction domain (UvrB_inter)

(159-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.623

100

0.5
  uvrB Streptococcus pneumoniae D39

49.623

100

0.5
  uvrB Streptococcus pneumoniae TIGR4

49.623

100

0.5