Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MPF99_RS01390 Genome accession   NZ_CP094130
Coordinates   295710..297686 (-) Length   658 a.a.
NCBI ID   WP_245059545.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe053     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 290710..302686
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPF99_RS01365 (MPF99_01365) - 290792..291184 (+) 393 WP_000656175.1 4Fe-4S dicluster domain-containing protein -
  MPF99_RS01370 (MPF99_01370) - 291195..292418 (+) 1224 WP_001097079.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  MPF99_RS01375 (MPF99_01375) - 292431..293375 (+) 945 WP_000238169.1 thiamine pyrophosphate-dependent enzyme -
  MPF99_RS01380 (MPF99_01380) purB 293485..294807 (+) 1323 WP_245059093.1 adenylosuccinate lyase -
  MPF99_RS01385 (MPF99_01385) - 294878..295713 (+) 836 Protein_264 outer membrane protein -
  MPF99_RS01390 (MPF99_01390) uvrB 295710..297686 (-) 1977 WP_245059545.1 excinuclease ABC subunit UvrB Machinery gene
  MPF99_RS07890 - 297858..297932 (-) 75 Protein_266 histidinol dehydrogenase -
  MPF99_RS01395 (MPF99_01395) - 297936..298324 (-) 389 Protein_267 hypothetical protein -
  MPF99_RS07830 - 298357..298479 (+) 123 WP_280636810.1 hypothetical protein -
  MPF99_RS01400 (MPF99_01400) - 298892..299662 (-) 771 WP_180443486.1 HP1117 family Sel1-like repeat protein -
  MPF99_RS01405 (MPF99_01405) ggt 299945..301648 (-) 1704 WP_245059095.1 gamma-glutamyltransferase -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75985.55 Da        Isoelectric Point: 6.7308

>NTDB_id=575674 MPF99_RS01390 WP_245059545.1 295710..297686(-) (uvrB) [Helicobacter pylori strain Hpfe053]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIANINKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSAATSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLRLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKHLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEYDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKLHNITPKTVTRALEEELKLRDDEIKIAKVLKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRVL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=575674 MPF99_RS01390 WP_245059545.1 295710..297686(-) (uvrB) [Helicobacter pylori strain Hpfe053]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCACAAGCTATAGAAGCCTTAACGAAGAGCTT
AAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGGAGCGGTAAGACTTATACGATGGCTAATATCATCGCTA
ACATCAACAAGCCCACTCTGATCATGAGCCATAATAAGACCTTATGCGCGCAGCTTTATAGCGAGTTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGACTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGGTTGAGCGCAGCCACCTCACTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGTGCCTATAAGAGTTTTTTATTAAGGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGTTTTAGAGCGACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATCAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCTTTAGAAAGAAATGAAATCAAGCACTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAGTGAGAGGTTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TTTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGTATGATTTAG
AAATGATTAGTGCAACCGGTGTGTGTAAGGGTATTGAAAATTATGCGCGCCATTTTACAGGCAAAGCCCCTAATGAAACG
CCTTTTTGTTTGTTTGATTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGTGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCTACGCCCAATAAG
CTAGAATTAGAGCTTTCTAAGAAGAATGTTGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTTATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCCGAATGGGGCTTGAAAGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAACGAAATCACATCATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
TTTAAGAGAAGGGTTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCTAATGGCAAGGTTTTATTATACGCTAAAAAAATCACT
CAAAGCATGCAAAAAGCCTTTGAAATTACGAGCTACAGGCGCGCTAAGCAAGAAGAATTTAATAAGCTTCACAATATCAC
TCCCAAAACCGTTACTCGCGCTTTAGAAGAGGAGTTGAAATTAAGAGACGATGAGATTAAAATCGCTAAAGTCTTAAAAA
AAGACAAAATCCCTAAAAGCGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGATGAAATCGCTAAATTAAGAGTGCTTTAA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(554-595)

UvrB/uvrC motif (UVR)

(623-656)

Type III restriction enzyme, res subunit (ResIII)

(15-123)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

UvrB interaction domain (UvrB_inter)

(159-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.472

100

0.498
  uvrB Streptococcus pneumoniae D39

49.472

100

0.498
  uvrB Streptococcus pneumoniae TIGR4

49.472

100

0.498