Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   KOM03_RS10995 Genome accession   NZ_CP076450
Coordinates   2159159..2159815 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain GMEKP1     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2154159..2164815
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KOM03_RS10965 (KOM03_10965) oppF 2154689..2155606 (+) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -
  KOM03_RS10970 (KOM03_10970) - 2155713..2156900 (+) 1188 WP_079891086.1 putative glycoside hydrolase -
  KOM03_RS10975 (KOM03_10975) - 2157018..2157596 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  KOM03_RS10980 (KOM03_10980) spx 2157775..2158170 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  KOM03_RS10985 (KOM03_10985) - 2158227..2158883 (-) 657 WP_060562158.1 TerC family protein -
  KOM03_RS10995 (KOM03_10995) mecA 2159159..2159815 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  KOM03_RS11000 (KOM03_11000) - 2159966..2161126 (+) 1161 WP_060562159.1 competence protein CoiA family protein -
  KOM03_RS11005 (KOM03_11005) pepF 2161354..2163183 (+) 1830 WP_101536289.1 oligoendopeptidase F Regulator
  KOM03_RS11010 (KOM03_11010) - 2163221..2163388 (-) 168 WP_003155026.1 hypothetical protein -
  KOM03_RS11015 (KOM03_11015) spxH 2163674..2164576 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=575476 KOM03_RS10995 WP_003155032.1 2159159..2159815(+) (mecA) [Bacillus velezensis strain GMEKP1]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=575476 KOM03_RS10995 WP_003155032.1 2159159..2159815(+) (mecA) [Bacillus velezensis strain GMEKP1]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895