Detailed information NTG0575443

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: KOM03_RS02410
• Genome accession: NZ_CP076450
• Coordinates: 469581..470744 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain GMEKP1
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 464581..475744

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KOM03_RS02380 (KOM03_02380)	-	464846..465265 (-)	420	WP_025285352.1	TIGR03826 family flagellar region protein	-
KOM03_RS02385 (KOM03_02385)	comFC	465339..466028 (-)	690	WP_197714552.1	phosphoribosyltransferase family protein	Machinery gene
KOM03_RS02390 (KOM03_02390)	-	466034..466318 (-)	285	WP_003151389.1	competence protein ComFB	-
KOM03_RS02395 (KOM03_02395)	comFA	466376..467761 (-)	1386	WP_060562494.1	DEAD/DEAH box helicase	Machinery gene
KOM03_RS02400 (KOM03_02400)	-	467869..468717 (-)	849	WP_003151387.1	DegV family protein	-
KOM03_RS02405 (KOM03_02405)	degU	468815..469504 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
KOM03_RS02410 (KOM03_02410)	degS	469581..470744 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
KOM03_RS02415 (KOM03_02415)	-	470967..471614 (+)	648	WP_007614107.1	YigZ family protein	-
KOM03_RS02420 (KOM03_02420)	-	471619..472839 (+)	1221	WP_012118574.1	LCP family protein	-
KOM03_RS02425 (KOM03_02425)	-	472938..474014 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
KOM03_RS02430 (KOM03_02430)	-	474147..475343 (-)	1197	WP_060562493.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=575443 KOM03_RS02410 WP_007407484.1 469581..470744(-) (degS) [Bacillus velezensis strain GMEKP1]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=575443 KOM03_RS02410 WP_007407484.1 469581..470744(-) (degS) [Bacillus velezensis strain GMEKP1]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGTCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951