Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MPG25_RS01905 Genome accession   NZ_CP094121
Coordinates   383123..385099 (+) Length   658 a.a.
NCBI ID   WP_245018924.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe059     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 378123..390099
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG25_RS01890 (MPG25_01890) ggt 379218..380921 (+) 1704 WP_001254518.1 gamma-glutamyltransferase -
  MPG25_RS01895 (MPG25_01895) - 381208..381978 (+) 771 WP_245018922.1 HP1117 family Sel1-like repeat protein -
  MPG25_RS01900 (MPG25_01900) - 382880..383011 (+) 132 WP_245018923.1 histidinol dehydrogenase -
  MPG25_RS01905 (MPG25_01905) uvrB 383123..385099 (+) 1977 WP_245018924.1 excinuclease ABC subunit UvrB Machinery gene
  MPG25_RS01910 (MPG25_01910) - 385096..385928 (-) 833 Protein_375 outer membrane protein -
  MPG25_RS01915 (MPG25_01915) purB 385991..387313 (-) 1323 WP_000893801.1 adenylosuccinate lyase -
  MPG25_RS01920 (MPG25_01920) - 387423..388367 (-) 945 WP_000238169.1 thiamine pyrophosphate-dependent enzyme -
  MPG25_RS01925 (MPG25_01925) - 388380..389603 (-) 1224 WP_001097079.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  MPG25_RS01930 (MPG25_01930) - 389613..390005 (-) 393 WP_000656174.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 76039.52 Da        Isoelectric Point: 6.8655

>NTDB_id=575437 MPG25_RS01905 WP_245018924.1 383123..385099(+) (uvrB) [Helicobacter pylori strain Hpfe059]
MPLFDLKSHYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIITNINKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSAATSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYAASQFAVGNERLNLAIKSIEDELALRLKFFKEHDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSQKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKLHHITPKTVTRALEEELKLRDDEVKIAKALKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=575437 MPG25_RS01905 WP_245018924.1 383123..385099(+) (uvrB) [Helicobacter pylori strain Hpfe059]
ATGCCTTTATTTGATTTAAAAAGCCATTACCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCCTTAACGAAAAGCTT
GAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGGAGCGGTAAAACTTATACGATGGCTAATATCATCACTA
ACATCAACAAACCCACTCTGATCATGAGCCATAATAAGACCTTATGCGCACAGCTTTATAGCGAGTTTAAAGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATTTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGATTGAGCGCGGCCACCTCACTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGTGCTTATAAGAGCTTTTTACTCAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGTTTTAGAGCGACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATCAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCTTTAGAAAGAAATGAAATCAAACGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAATGAGAGACTGAATCTAGCCATTAAAAGCATTGAAGATGAACTCGC
TTTAAGATTGAAATTTTTTAAAGAGCATGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCGCAACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTTACAGGCAAAGCCCCTAATGAAACG
CCTTTTTGTTTGTTTGATTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAATTTGGGGGGATGTATGCGGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAATCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCTACGCCCAATAAG
CTAGAATTAGAGCTTTCTCAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTTATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCCGAATGGGGCTTGAAAGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAACGAAATCACATCATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
CTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCCAATGGCAAGGTTTTATTATACGCTAAAAAAATCACC
CAAAGCATGCAAAAAGCCTTTGAAATTACGAGCTACAGGCGCGCTAAGCAAGAAGAGTTTAATAAGCTTCATCATATCAC
CCCCAAGACCGTTACTCGCGCTTTAGAAGAGGAGTTGAAATTAAGAGACGATGAGGTTAAAATCGCTAAAGCCTTAAAAA
AGGACAAAATCCCTAAAAGCGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGATGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(623-657)

Type III restriction enzyme, res subunit (ResIII)

(15-123)

UvrB interaction domain (UvrB_inter)

(159-248)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

Ultra-violet resistance protein B (UvrB)

(554-595)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.321

100

0.497
  uvrB Streptococcus pneumoniae TIGR4

49.321

100

0.497
  uvrB Streptococcus pneumoniae D39

49.321

100

0.497