Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MPG74_RS02110 Genome accession   NZ_CP094120
Coordinates   420306..422282 (+) Length   658 a.a.
NCBI ID   WP_245069838.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe061     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 415306..427282
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG74_RS02095 (MPG74_02095) flgK 415321..417141 (+) 1821 WP_245069836.1 flagellar hook-associated protein FlgK -
  MPG74_RS02100 (MPG74_02100) ggt 417346..419049 (+) 1704 WP_180398149.1 gamma-glutamyltransferase -
  MPG74_RS02105 (MPG74_02105) - 419316..420086 (+) 771 WP_245069837.1 tetratricopeptide repeat protein -
  MPG74_RS02110 (MPG74_02110) uvrB 420306..422282 (+) 1977 WP_245069838.1 excinuclease ABC subunit UvrB Machinery gene
  MPG74_RS02115 (MPG74_02115) - 422293..423126 (-) 834 WP_245069839.1 outer membrane protein -
  MPG74_RS02120 (MPG74_02120) purB 423187..424509 (-) 1323 WP_245069840.1 adenylosuccinate lyase -
  MPG74_RS02125 (MPG74_02125) - 424619..425563 (-) 945 WP_245069841.1 thiamine pyrophosphate-dependent enzyme -
  MPG74_RS02130 (MPG74_02130) - 425576..426799 (-) 1224 WP_245069842.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  MPG74_RS02135 (MPG74_02135) - 426810..427202 (-) 393 WP_000656168.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 76046.58 Da        Isoelectric Point: 6.9241

>NTDB_id=575400 MPG74_RS02110 WP_245069838.1 420306..422282(+) (uvrB) [Helicobacter pylori strain Hpfe061]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIAQINKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSAATSLLGYDDVIVIASVSANYGLGNPEEYLKVMERI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDTLERNEIKRLDSV
MLYAASQFAVGNERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYTEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKLHHITPKTVTRALEEELKLRDDEVKIAKALKKDKILKSEREKIIKELDKKMRECAKNL
DFEEAVRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=575400 MPG74_RS02110 WP_245069838.1 420306..422282(+) (uvrB) [Helicobacter pylori strain Hpfe061]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCCCAAGCTATAGAAGCCTTAACGAAAAGCTT
GAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACGGGGAGCGGTAAAACTTATACGATGGCCAATATCATCGCTC
AAATCAATAAACCCACTCTGATCATGAGCCATAATAAGACCTTATGCGCGCAACTTTATAGCGAGTTTAAGGCGTTTTTT
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGATTGAGCGCGGCCACCTCACTTTTAGGTTATGATG
ATGTGATTGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAGAATC
AAAGTGGGCGAGAAGCGCGCTTATAAGAGTTTTTTACTCAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGTTTTAGAGCGACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATTAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACACTTTAGAAAGAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCTGTAGGGAATGAGAGGTTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TCTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCGCAACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTTACAGGCAAAGCCCCTAATGAAACG
CCTTTTTGTTTGTTTGATTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCATTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCCACGCCCAATAAG
CTAGAATTAGAGCTTTCTAAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTTATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATACTGAATGGGGCTTGAAAGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGAAATCACATCATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGAATCAATCT
CTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGGCGAGCTGCTAGAAACGCTAATGGCAAGGTTTTATTATACGCTAAAAAAATCACC
CAAAGCATGCAAAAAGCCTTTGAAATTACGAGCTACAGGCGCGCTAAGCAAGAAGAGTTTAATAAGCTTCATCATATCAC
TCCCAAAACCGTTACTCGCGCTTTAGAAGAGGAGTTGAAATTAAGAGATGATGAGGTTAAAATCGCTAAAGCCTTAAAAA
AGGACAAAATACTTAAAAGCGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GATTTTGAAGAAGCGGTGCGTTTGAGAGACGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

Type III restriction enzyme, res subunit (ResIII)

(15-120)

UvrB interaction domain (UvrB_inter)

(160-248)

Ultra-violet resistance protein B (UvrB)

(554-595)

UvrB/uvrC motif (UVR)

(623-657)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.17

100

0.495
  uvrB Streptococcus pneumoniae TIGR4

49.17

100

0.495
  uvrB Streptococcus pneumoniae D39

49.17

100

0.495