Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MPG41_RS01895 Genome accession   NZ_CP094109
Coordinates   380160..382136 (+) Length   658 a.a.
NCBI ID   WP_245068088.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe072     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 375160..387136
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG41_RS01880 (MPG41_01880) ggt 376257..377960 (+) 1704 WP_245068084.1 gamma-glutamyltransferase -
  MPG41_RS01885 (MPG41_01885) - 378248..379018 (+) 771 WP_245068086.1 tetratricopeptide repeat protein -
  MPG41_RS01890 (MPG41_01890) - 379916..380047 (+) 132 WP_096530768.1 histidinol dehydrogenase -
  MPG41_RS01895 (MPG41_01895) uvrB 380160..382136 (+) 1977 WP_245068088.1 excinuclease ABC subunit UvrB Machinery gene
  MPG41_RS01900 (MPG41_01900) - 382133..382966 (-) 834 WP_245068090.1 outer membrane protein -
  MPG41_RS01905 (MPG41_01905) purB 383037..384359 (-) 1323 WP_245068092.1 adenylosuccinate lyase -
  MPG41_RS01910 (MPG41_01910) - 384469..385413 (-) 945 WP_120836498.1 thiamine pyrophosphate-dependent enzyme -
  MPG41_RS01915 (MPG41_01915) - 385426..386649 (-) 1224 WP_245068094.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  MPG41_RS01920 (MPG41_01920) - 386659..387051 (-) 393 WP_245068096.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75935.44 Da        Isoelectric Point: 6.7808

>NTDB_id=575076 MPG41_RS01895 WP_245068088.1 380160..382136(+) (uvrB) [Helicobacter pylori strain Hpfe072]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIANTNKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSAATSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALEKNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKQNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKVRYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKLHHITPKTVTRALEEELKLRDDEIKIAKALKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=575076 MPG41_RS01895 WP_245068088.1 380160..382136(+) (uvrB) [Helicobacter pylori strain Hpfe072]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCCTTAACGAAAAGCTT
GAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGGAGCGGTAAAACTTATACGATGGCCAATATCATCGCTA
ATACCAACAAACCCACTCTGATCATGAGCCATAATAAGACCTTATGCGCGCAGCTCTATAGCGAGTTTAAAGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGACTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGGTTGAGCGCGGCCACCTCACTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCGCTTATAAGAGCTTTTTATTAAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGTTTTAGAGCGACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATCAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCTTTAGAAAAAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAGTGAGAGGTTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TTTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCGCGACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTTACAGGCAAAGCCCCCAATGAAACG
CCTTTTTGTTTGTTTGATTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCTACGCCCAATAAG
CTAGAATTAGAGCTTTCTAAACAGAATGTCGCTGAGCAAATCATCCGTCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTTATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGTTTGAAGGTGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGAAATCACATCATTCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
CTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCTAATGGCAAGGTTTTATTATACGCTAAAAAAATCACC
CAAAGCATGCAAAAAGCCTTTGAAATTACGAGCTACAGGCGCGCTAAGCAAGAAGAGTTTAATAAGCTTCATCATATCAC
CCCCAAAACCGTTACTCGTGCTTTAGAAGAGGAGTTGAAATTAAGAGACGATGAGATTAAAATCGCTAAAGCCTTAAAAA
AGGACAAAATCCCTAAAAGTGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGATGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(159-248)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

UvrB/uvrC motif (UVR)

(623-657)

Ultra-violet resistance protein B (UvrB)

(554-595)

Type III restriction enzyme, res subunit (ResIII)

(15-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.623

100

0.5
  uvrB Streptococcus pneumoniae D39

49.623

100

0.5
  uvrB Streptococcus pneumoniae TIGR4

49.623

100

0.5