Detailed information    

insolico Bioinformatically predicted

Overview

Name   scnR   Type   Regulator
Locus tag   KNZ78_RS19140 Genome accession   NZ_CP076377
Coordinates   4135449..4136156 (+) Length   235 a.a.
NCBI ID   WP_009888460.1    Uniprot ID   A0A9Q8EBL8
Organism   Clostridioides difficile strain S-0352     
Function   regulate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 4130449..4141156
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KNZ78_RS19115 (KNZ78_19115) cdd1 4131244..4131489 (+) 246 WP_021364306.1 protein Cdd1 -
  KNZ78_RS19120 (KNZ78_19120) - 4131707..4131976 (-) 270 WP_003426848.1 DUF3795 domain-containing protein -
  KNZ78_RS19125 (KNZ78_19125) - 4132854..4133591 (-) 738 WP_003439186.1 ABC transporter permease -
  KNZ78_RS19130 (KNZ78_19130) - 4133603..4134364 (-) 762 WP_021372951.1 ABC transporter permease -
  KNZ78_RS19135 (KNZ78_19135) - 4134364..4135287 (-) 924 WP_170320070.1 ABC transporter ATP-binding protein -
  KNZ78_RS19140 (KNZ78_19140) scnR 4135449..4136156 (+) 708 WP_009888460.1 response regulator transcription factor Regulator
  KNZ78_RS19145 (KNZ78_19145) - 4136201..4137607 (+) 1407 WP_021364310.1 sensor histidine kinase -
  KNZ78_RS19150 (KNZ78_19150) - 4139406..4139795 (+) 390 WP_003426867.1 BlaI/MecI/CopY family transcriptional regulator -
  KNZ78_RS19155 (KNZ78_19155) - 4140529..4140999 (+) 471 WP_003439176.1 VOC family protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26716.17 Da        Isoelectric Point: 6.1467

>NTDB_id=574878 KNZ78_RS19140 WP_009888460.1 4135449..4136156(+) (scnR) [Clostridioides difficile strain S-0352]
MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAVRVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIP
VIFLSARGEDEDRLIGLGLGADDYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPSTPKHLITVRGLGYKLMIN

Nucleotide


Download         Length: 708 bp        

>NTDB_id=574878 KNZ78_RS19140 WP_009888460.1 4135449..4136156(+) (scnR) [Clostridioides difficile strain S-0352]
ATGGAGTCAATAAAAGATAAAAAAATACTTGTGGTTGATGACCACAAGGAATTATTAAAAATGATAGATGAAATCCTGAG
AAAAGAGGGGTTTAGTAGAGTATTTTTAGCATCAAGTTATGAGGAAGCTGTTAGGGTATTTAGAAATGTAAAGCCAGATT
GTGCAATTTTAGATGTTGTATTGCCAGATGGAGATGGTTTTTCTATTATGAGAAAAATTAGAGAGACATCTAAAATACCA
GTGATTTTTCTCTCTGCAAGAGGTGAAGATGAAGATAGATTGATTGGTTTGGGCTTAGGGGCTGACGATTATATAGTAAA
GCCATTTTTACCAAAGGAACTTACTTTAAGGCTTGTGGGTATATTAAATCGTGTATATGTGCCTATAGAAGAAGAGGAGT
TGCCAGTATTTAAACTGGGAGATTCTGTTGTTGTGAATTTAAATAGTGCATGTGTTGAGAAAGATGGGCAAGAGATTTCT
TTAACAGCTAAAGAGCATTCGTTGCTTTTAAAGTTGTATGAAAATAAAGGGAGAATTGTTACTAATGATTCACTATGTCA
AGCCATTTGGGGAGATGATATGTATGGATATGAAAATACCCTTATGGTTCATGTTAGAAGGGTTAGAGAGAAGATAGAAA
AAACTCCATCTACACCTAAACATCTTATTACAGTAAGAGGTCTTGGATATAAGTTGATGATTAATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-232)

Response regulator receiver domain (Response_reg)

(9-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  scnR Streptococcus mutans UA159

48.918

98.298

0.481
  micA Streptococcus pneumoniae Cp1015

40

100

0.4
  vicR Streptococcus mutans UA159

38.362

98.723

0.379