Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MPG15_RS01890 Genome accession   NZ_CP094087
Coordinates   380147..382123 (+) Length   658 a.a.
NCBI ID   WP_127990755.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe093     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 375147..387123
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG15_RS01870 (MPG15_01870) ggt 376240..377943 (+) 1704 WP_075646514.1 gamma-glutamyltransferase -
  MPG15_RS01875 (MPG15_01875) - 378227..378997 (+) 771 WP_245079654.1 HP1117 family Sel1-like repeat protein -
  MPG15_RS01880 (MPG15_01880) - 379152..379416 (+) 265 Protein_365 hypothetical protein -
  MPG15_RS01885 (MPG15_01885) - 379899..380030 (+) 132 WP_180648216.1 histidinol dehydrogenase -
  MPG15_RS01890 (MPG15_01890) uvrB 380147..382123 (+) 1977 WP_127990755.1 excinuclease ABC subunit UvrB Machinery gene
  MPG15_RS01895 (MPG15_01895) - 382134..382967 (-) 834 WP_245079655.1 outer membrane protein -
  MPG15_RS01900 (MPG15_01900) purB 383029..384351 (-) 1323 WP_245079656.1 adenylosuccinate lyase -
  MPG15_RS01905 (MPG15_01905) - 384461..385405 (-) 945 WP_000238169.1 thiamine pyrophosphate-dependent enzyme -
  MPG15_RS01910 (MPG15_01910) - 385418..386641 (-) 1224 WP_001097080.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  MPG15_RS01915 (MPG15_01915) - 386652..387044 (-) 393 WP_140543980.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75947.50 Da        Isoelectric Point: 6.9241

>NTDB_id=574429 MPG15_RS01890 WP_127990755.1 380147..382123(+) (uvrB) [Helicobacter pylori strain Hpfe093]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIAQINKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSAATSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKLHHITPKTVTRALEEELKLRDDEVKIAKALKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=574429 MPG15_RS01890 WP_127990755.1 380147..382123(+) (uvrB) [Helicobacter pylori strain Hpfe093]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCCTTAACGAAGAGCTT
AAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGGAGCGGTAAAACTTATACGATGGCTAATATCATCGCTC
AAATCAACAAGCCCACTCTGATCATGAGCCATAATAAGACCTTATGCGCGCAGCTTTATAGCGAATTTAAGGCATTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGACTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGGTTGAGCGCAGCCACCTCACTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCGCTTATAAGAGCTTTTTATTAAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGCTTTAGGGCGACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAGTTTATTAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCTTTAGAAAGAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAGTGAGAGATTGAATTTAGCTATTAAAAGCATTGAAGATGAACTCGC
TTTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGTGCAACCGGTGTGTGTAAGGGCATTGAAAATTACGCACGCCATTTTACAGGCAAAGCCCCTAATGAAACG
CCTTTTTGCTTGTTTGATTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGAGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCTGCCACGCCCAATAAG
CTAGAATTAGAGCTTTCTAAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAGATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTTATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCCGAATGGGGCTTGAAAGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAACGAAATCACATCATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
CTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCCAATGGCAAGGTTTTATTATACGCTAAAAAAATCACC
CAAAGCATGCAAAAAGCCTTTGAAATTACGAGTTACAGGCGCGCTAAGCAAGAAGAATTCAATAAGCTTCATCATATCAC
CCCCAAAACCGTTACTCGCGCTTTAGAAGAGGAGTTGAAATTAAGAGACGATGAGGTTAAAATCGCTAAAGCCTTAAAAA
AAGACAAAATACCTAAAAGCGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGATGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(159-248)

UvrB/uvrC motif (UVR)

(623-657)

Type III restriction enzyme, res subunit (ResIII)

(15-123)

Ultra-violet resistance protein B (UvrB)

(554-595)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.321

100

0.497
  uvrB Streptococcus pneumoniae D39

49.321

100

0.497
  uvrB Streptococcus pneumoniae TIGR4

49.321

100

0.497