Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MPG46_RS01930 Genome accession   NZ_CP094066
Coordinates   381861..383837 (+) Length   658 a.a.
NCBI ID   WP_245014799.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe110     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 376861..388837
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG46_RS01910 (MPG46_01910) ggt 377949..379652 (+) 1704 WP_245014561.1 gamma-glutamyltransferase -
  MPG46_RS01915 (MPG46_01915) - 379936..380706 (+) 771 WP_245014562.1 tetratricopeptide repeat protein -
  MPG46_RS01920 (MPG46_01920) - 381021..381191 (-) 171 WP_245014563.1 hypothetical protein -
  MPG46_RS01925 (MPG46_01925) - 381224..381811 (+) 588 Protein_373 hypothetical protein -
  MPG46_RS01930 (MPG46_01930) uvrB 381861..383837 (+) 1977 WP_245014799.1 excinuclease ABC subunit UvrB Machinery gene
  MPG46_RS01935 (MPG46_01935) - 383848..384681 (-) 834 WP_245014564.1 outer membrane protein -
  MPG46_RS01940 (MPG46_01940) purB 384752..386074 (-) 1323 WP_245014565.1 adenylosuccinate lyase -
  MPG46_RS01945 (MPG46_01945) - 386183..387127 (-) 945 WP_245014566.1 thiamine pyrophosphate-dependent enzyme -
  MPG46_RS01950 (MPG46_01950) - 387140..388363 (-) 1224 WP_001097078.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  MPG46_RS01955 (MPG46_01955) - 388373..388765 (-) 393 WP_000656173.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75947.54 Da        Isoelectric Point: 7.0841

>NTDB_id=573899 MPG46_RS01930 WP_245014799.1 381861..383837(+) (uvrB) [Helicobacter pylori strain Hpfe110]
MPLFDLKSPYPPAGDQPKAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIAQINKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSAATSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKLHHITPKTVTRALEEELKLRDDEVKIAKALKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=573899 MPG46_RS01930 WP_245014799.1 381861..383837(+) (uvrB) [Helicobacter pylori strain Hpfe110]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCAAAAGCCATAGAAGCCTTAACGAAGAGCTT
AAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGGAGCGGTAAGACTTATACGATGGCCAATATCATCGCTC
AAATCAATAAACCCACTCTGATCATGAGCCATAATAAGACCTTATGCGCGCAGCTTTATAGCGAGTTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGACGATTTAGAGCGTTTGAGGTTGAGTGCGGCCACCTCACTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCGCTTATAAGAGCTTTTTATTAAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGCTTCAGGGCGACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATCAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCTTTAGAAAGAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAGTGAGAGACTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TTTAAGATTGAAATTTTTTAAAGAGCAAGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCGCAACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTTACAGGCAAAGCCCCTAATGAAACG
CCTTTTTGCTTGTTTGATTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGAGGGATGTATGCGGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCTACGCCCAATAAG
CTAGAATTAGAGCTTTCTAAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTCATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATACTATGCTGAATGGGGCTTGAAGGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAACGAAATCACATCATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
TTTAAGAGAAGGATTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCCAATGGCAAGGTTTTATTATACGCTAAAAAAATCACC
CAAAGCATGCAAAAAGCCTTTGAAATTACGAGCTACAGGCGTGCTAAGCAAGAAGAATTTAATAAGCTTCATCATATCAC
CCCCAAAACCGTTACTCGCGCTTTAGAAGAGGAGTTGAAATTAAGAGACGATGAGGTTAAAATCGCTAAAGCCTTAAAAA
AAGACAAAATACCTAAAAGCGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGCTTGAGAGATGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(159-248)

UvrB/uvrC motif (UVR)

(623-657)

Type III restriction enzyme, res subunit (ResIII)

(15-123)

Ultra-violet resistance protein B (UvrB)

(554-595)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.17

100

0.495
  uvrB Streptococcus pneumoniae D39

49.17

100

0.495
  uvrB Streptococcus pneumoniae TIGR4

49.17

100

0.495