Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MPG66_RS01905 Genome accession   NZ_CP094056
Coordinates   379268..381244 (+) Length   658 a.a.
NCBI ID   WP_245025777.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe124     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 374268..386244
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG66_RS01890 (MPG66_01890) ggt 375388..377091 (+) 1704 WP_130796046.1 gamma-glutamyltransferase -
  MPG66_RS01895 (MPG66_01895) - 377352..378122 (+) 771 WP_041201537.1 HP1117 family Sel1-like repeat protein -
  MPG66_RS01900 (MPG66_01900) - 378628..379217 (+) 590 Protein_369 DUF1542 domain-containing protein -
  MPG66_RS01905 (MPG66_01905) uvrB 379268..381244 (+) 1977 WP_245025777.1 excinuclease ABC subunit UvrB Machinery gene
  MPG66_RS01910 (MPG66_01910) - 381255..382088 (-) 834 WP_245025345.1 outer membrane protein -
  MPG66_RS01915 (MPG66_01915) purB 382151..383473 (-) 1323 WP_245025347.1 adenylosuccinate lyase -
  MPG66_RS01920 (MPG66_01920) - 383583..384527 (-) 945 WP_245025349.1 thiamine pyrophosphate-dependent enzyme -
  MPG66_RS01925 (MPG66_01925) - 384540..385763 (-) 1224 WP_001097080.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  MPG66_RS01930 (MPG66_01930) - 385774..386166 (-) 393 WP_000656168.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 76019.56 Da        Isoelectric Point: 6.7808

>NTDB_id=573575 MPG66_RS01905 WP_245025777.1 379268..381244(+) (uvrB) [Helicobacter pylori strain Hpfe124]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIAQINKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSAATSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSQKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRTKQEEFNKLHHITPKTVTRVLEEELKLRDDEIKIAKALKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=573575 MPG66_RS01905 WP_245025777.1 379268..381244(+) (uvrB) [Helicobacter pylori strain Hpfe124]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCCTTAACGAAGAGCTT
GAAAAATAACAACCATTATCAAACTTTAGTGGGAGTTACAGGGAGCGGTAAGACTTATACGATGGCTAATATCATCGCTC
AAATCAACAAACCCACTCTGATCATGAGCCATAATAAGACCTTATGCGCGCAGCTCTATAGCGAGTTTAAGGCGTTTTTC
CCACATAATAGGGTGGAGTATTTTATCTCCCACTTTGACTACTATCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGATTGAGCGCGGCCACCTCACTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCGCTTATAAGAGTTTTTTATTAAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGTTTTAGGGCGACCGGAGAATGCGTGGATATTTTCCCTGCTTATAATGACGCTGAATTTATCAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCTTTAGAAAGAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCTGTAGGGAGTGAGAGGTTGAATTTAGCCATTAAAAGTATTGAAGATGAACTCGC
TTTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCGCAACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTTACAGGCAAAGCTCCTAATGAAACG
CCTTTTTGCTTGTTTGATTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCCACGCCCAATAAG
CTAGAATTAGAGCTTTCTCAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAGTTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTTATCA
CCACGCTCACTAAAAAAATGGCGGAAGAATTGTGCAAATATTATGCCGAATGGGGCTTGAAAGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGGAATCACATCATCCGTTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
TTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGTCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCTAATGGCAAGGTTTTATTATACGCTAAAAAAATCACC
CAAAGCATGCAAAAAGCTTTTGAAATTACGAGCTACAGGCGCACTAAGCAAGAAGAGTTTAATAAGCTTCATCATATCAC
CCCCAAAACCGTTACTCGCGTTTTAGAAGAGGAATTGAAATTAAGAGACGATGAGATTAAAATCGCTAAAGCCTTAAAAA
AGGACAAAATCCCTAAAAGCGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTA
GATTTTGAAGAAGCGATGCGTTTGAGAGATGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(623-657)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

Ultra-violet resistance protein B (UvrB)

(554-593)

UvrB interaction domain (UvrB_inter)

(159-248)

Type III restriction enzyme, res subunit (ResIII)

(15-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.472

100

0.498
  uvrB Streptococcus pneumoniae TIGR4

49.472

100

0.498
  uvrB Streptococcus pneumoniae D39

49.472

100

0.498